THE LEVELS OF OSTEOPROTEGERIN AND ADIPOKINES IN WOMEN WITH HYPOTHYROIDISM


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Abstract

Patients with hypothyroidism were examined for the levels of osteoprotegerin, resistin, leptin, and adiponectin and found to have atherogenic dyslipidemia in the presence of enhanced insulin resistance and compensatorily elevated insulin levels. The concentrations of leptin, resistin, and osteoprotegerin were increased and the level of adiponectin was decreased in the patients with thyroid hypofunction. The found correlations of leptin and adiponectin levels with fat metabolic parameters permitted the authors to suggest that leptin and adiponectin play a certain role in the development of dyslipidemia in hypothyroidism.

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About the authors

N. Verbovaya

Samara State Medical University

Professor

I. Kapralova

Samara State Medical University

A. Verbovoy

Samara State Medical University

Email: andreyy.verbovoyy@rambler.ru
Professor

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