Cellular chronoblockers in multimodal programmes for the prevention of cognitive deficit
- Authors: Gashimova U.1, Korshun E.2, Zhaboeva S.3, Satardinova E.4
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Affiliations:
- Western University of Baku
- Institute for Advanced Training, Federal Biomedical Agency
- Kazan State Medical University
- Irkutsk State Medical Academy of Postgraduate Education
- Issue: Vol 29, No 9 (2018)
- Pages: 43-47
- Section: Articles
- URL: https://journals.eco-vector.com/0236-3054/article/view/117320
- DOI: https://doi.org/10.29296/25877305-2018-09-09
- ID: 117320
Cite item
Abstract
The paper considers the target points of application of cellular chronoblockers (succinic acid, guarana, taurine, selenium, L-arginine, and ß-alanine) in the multimodal programs to prevent cognitive deficit. It shows the effects of these substances in improving cognitive abilities.
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About the authors
U. Gashimova
Western University of BakuProfessor
E. Korshun
Institute for Advanced Training, Federal Biomedical Agency
S. Zhaboeva
Kazan State Medical University
E. Satardinova
Irkutsk State Medical Academy of Postgraduate Education
References
- Ильницкий А.Н., Прощаев К.И., Трофимова С.В. и др. Превентивная гериатрия, или антивозрастная медицина // Успехи геронтол. - 2015; 28 (3): 589-92.
- Paul S., Gallagher E., Liow J. et al. Building a database for brain 18 kDa translocator protein imaged using [11 C]PBR28 in healthy subjects // J. Cereb. Blood Flow Metab. - 2018; 1: 271-8.
- Ильницкий А.Н., Прощаев К.И., Коршун Е.И. Клеточные хроноблокаторы и старение головного мозга // Геронтология. - 2017; 1: (электронное издание). http://gerontology.su/magazines?text=231
- Peters R. Ageing and the brain // Postgrad. Med. J. - 2016; 82: 84-8.
- Ильницкий А.Н., Прощаев К.И., Коршун Е.И. Синдром хронического информационного истощения (squeezed-синдром) в антивозрастной медицине // Эстетическая медицина. - 2017; 17 (1): 95-9.
- Collins R., Patel K., Putnam W. et al. Oncometabolites: A New Paradigm for Oncology, Metabolism, and the Clinical Laboratory // Clin. Chem. - 2017; 63 (12): 1812-20.
- Spencer J. The impact of fruit flavonoids on memory and Cognition // Br. J. Nutr. - 2010; 104 (Suppl. 3): 40-7.
- Bazhanova E., Anisimov V., Sukhanov D. et al. Comparative experimental study of the influence of drugs that improve brain metabolism (angiogen, cytoflavin) on neuronal apoptosis and function of cerebral cortex during aging // Eksp. Klin. Farmakol. - 2015; 78 (2): 3-9.
- Stetsura Y., Sholomov I., Schukovsky N. et al. The effect of the succinic acid preparation on the dynamics of neurological and emotional disturbances in patients with dorsopathy // Zh. Nevrol. Psikhiatr. Im. S.S. Korsakova. - 2015; 115 (3): 45-8.
- Harris R., Dunnett M., Greenhaf P. Carnosine and Taurine contents in individual fibres of human vastus lateralis muscle // J. Sport Sci. - 1998; 16: 639-43.
- Rosa F., Freitas E., Deminice R. et al. Oxidative stress and inflammation in obesity after taurine supplementation: a double-blind, placebo-controlled study // Eur. J. Nutr. - 2013; 5: 33-8.
- Wickelgren I. The aging brain: for the cortex, neuron loss may be less than thought // Science. - 2013; 273: 48-50.
- Hill C., Harris R., Kim H. et al. Influence of beta-alanine supplementation on skeletal muscle carnosine concentrations and high intensity cycling capacity // Amino Acids. - 2007; 32 (2): 225-33.
- Hobson R., Saunders B., Ball G. et al. Effects of ß-alanine supplementation on exercise performance: a meta-analysis // Amino Acids. - 2012; 43 (1): 25.
- Hoffman J., Ratamess N., Ross R. Beta-alanine and the hormonal response to exercise // Int. J. Sports Med. - 2008; 29 (12): 952-8.
- Stout J., Graves B., Smith A. et al. The effect of beta-alanine supplementation on neuromuscular fatigue in elderly (55-92 Years): a double-blind randomized study // J. Int. Soc. Sports Nutr. - 2008; 7 (5): 21.
- De Domenico S., Giudetti A. Nutraceutical intervention in ageing brain // J. Gerontol. Geriatr. - 2017; 65: 79-92.
- Navarro A., Boveris A. Brain mitochondrial dysfunction in aging, neurodegeneration, and Parkinson’s disease // Front Aging Neurosci. - 2010; 5: 676-9.
- Picard M., McEwen B. Mitochondria impact brain function and cognition // Proc. Natl. Acad. Sci USA. - 2014; 111: 7-8.
- Schuitemaker A., van der Doef T., Boellaard R. et al. Microglial activation in healthy aging // Neurobiol. Aging. - 2012; 33: 1067-72.