Comparative analysis of quantitative polymerase chain reaction and culture methods for diagnosing urogenital infections and assessing vaginal microflora

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Abstract

Modern diagnosis of infectious-inflammatory diseases and imbalances in the female urogenital tract microbiota requires selecting an optimal laboratory method. Based on a review of the literature, a comparative analysis of quantitative polymerase chain reaction and culture (microbiological) methods is conducted. The advantages and disadvantages of the methods are considered. Rational use of both methods, guided by their strengths and limitations, is key to effective clinical practice.

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About the authors

V. Kaptilnyy

I.M. Sechenov First Moscow State Medical University, Ministry of Health of Russia (Sechenov University)

Author for correspondence.
Email: rtchilova@gmail.com
ORCID iD: 0000-0002-2656-132X
SPIN-code: 4312-3455

Candidate of Medical Sciences, Professor

Russian Federation

R. Chilova

I.M. Sechenov First Moscow State Medical University, Ministry of Health of Russia (Sechenov University)

Email: rtchilova@gmail.com
ORCID iD: 0000-0001-6331-3109
SPIN-code: 4137-4848

MD

Russian Federation

D. Lystsev

I.M. Sechenov First Moscow State Medical University, Ministry of Health of Russia (Sechenov University)

Email: rtchilova@gmail.com
ORCID iD: 0009-0006-3826-3174
Russian Federation

M. Poznyak

I.M. Sechenov First Moscow State Medical University, Ministry of Health of Russia (Sechenov University)

Email: rtchilova@gmail.com
ORCID iD: 0009-0006-8217-0784
Russian Federation

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