Фоновые и предраковые заболевания вульвы и влагалища: современные представления, диагностика, лечение и реабилитация

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Аннотация

Статья посвящена современным аспектам классификации, эпидемиологии, патогенеза, диагностики, лечения и реабилитации фоновых и предраковых заболеваний вульвы и влагалища. Особое внимание уделено стратификации интраэпителиальных неоплазий по ВПЧ-статусу, роли иммуногистохимических маркеров (p16, p53) и молекулярно-генетических характеристик в прогностической оценке. Представлены актуальные данные по клиническим проявлениям и диагностическим подходам, включая неинвазивные методы, рефлективную конфокальную микроскопию. Обобщены современные терапевтические стратегии с анализом эффективности имиквимода, фотодинамической терапии, CO2-лазера и хирургических вмешательств. Описаны подходы к мультидисциплинарной реабилитации, включая использование вагинальных расширителей, физиотерапии тазового дна, психосексуальной поддержки и телемедицинских технологий. Акцент сделан на необходимости междисциплинарного и персонализированного подхода к ведению данной категории пациенток с целью повышения качества жизни и профилактики малигнизации.

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Об авторах

А. Г. Солопова

Первый МГМУ им. И.М. Сеченова Минздрава России (Сеченовский Университет)

Автор, ответственный за переписку.
Email: antoninasolopova@yandex.ru
ORCID iD: 0000-0002-7456-2386
SPIN-код: 5278-0465

доктор медицинских наук, профессор

Россия, Москва

А. В. Воробьев

Первый МГМУ им. И.М. Сеченова Минздрава России (Сеченовский Университет)

Email: antoninasolopova@yandex.ru
ORCID iD: 0000-0002-4509-9281
SPIN-код: 5806-7062

кандидат медицинских наук, доцент

 

 

Россия, Москва

Д. Х. Хизроева

Первый МГМУ им. И.М. Сеченова Минздрава России (Сеченовский Университет)

Email: antoninasolopova@yandex.ru
ORCID iD: 0000-0002-0725-9686
SPIN-код: 8225-4976

доктор медицинских наук, профессор

Россия, Москва

А. Е. Иванов

Городская клиническая больница им. С.С. Юдина Департамента здравоохранения города Москвы

Email: antoninasolopova@yandex.ru
ORCID iD: 0000-0003-1115-3144

кандидат медицинских наук

Россия, Москва

Д. О. Уткин

Городская клиническая больница им. С.С. Юдина Департамента здравоохранения города Москвы

Email: antoninasolopova@yandex.ru
ORCID iD: 0000-0002-6620-2073
SPIN-код: 2368-7127

кандидат медицинских наук

Россия, Москва

О. С. Гридасова

Клиника R.T.H.

Email: antoninasolopova@yandex.ru
ORCID iD: 0009-0005-1775-9923
Россия, Москва

Д. С. Царелунга

Первый МГМУ им. И.М. Сеченова Минздрава России (Сеченовский Университет)

Email: antoninasolopova@yandex.ru
ORCID iD: 0009-0001-9930-4746
Россия, Москва

К. Н. Григорьева

Первый МГМУ им. И.М. Сеченова Минздрава России (Сеченовский Университет)

Email: antoninasolopova@yandex.ru
ORCID iD: 0000-0002-7756-8935
SPIN-код: 6031-2462

кандидат медицинских наук

Россия, Москва

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