Hyperuricemia: pathophysiological aspects, significance in clinical practice
- 作者: Kunitskaya N.A1, Aryev A.L1, Polyakova V.V1, Dobritsa V.P1
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隶属关系:
- I.I. Mechnikov North-West State Medical University Russian Ministry of Health
- 期: 卷 33, 编号 2 (2022)
- 页面: 69-77
- 栏目: Articles
- URL: https://journals.eco-vector.com/0236-3054/article/view/114579
- DOI: https://doi.org/10.29296/25877305-2022-02-12
- ID: 114579
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详细
Hyperuricemia, an increase in serum uric acid (UA) concentration above 420 pmol/L for men and 360 pmol/L for women (clinical guidelines of the Russian Association of Rheumatologists (2018)), is a common problem in clinical practice. Existing clinical guidelines regulate the management of patients with symptomatic hyperuricemia, primarily gout, urolithiasis, and acute urate nephropathy, but less attention is given to the primary prevention of these diseases and to the treatment of asymptomatic hyperuricemia. It is also known that UA and, consequently, hyperuricemia are also important in the development of cardiovascular diseases, primarily hypertension, heart failure and chronic kidney disease, and meanwhile, the treatment of asymptomatic hyperuricemia in these patients still depends on the doctor’s opinion. This review analyzed current trends in the treatment of patients with symptomatic and asymptomatic hyperuricemia according to current views on the role of UA in the development of gout, renal, cardiovascular, and other diseases.
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作者简介
N. Kunitskaya
I.I. Mechnikov North-West State Medical University Russian Ministry of Health
Email: scvssd@yandex.ru
Professor
A. Aryev
I.I. Mechnikov North-West State Medical University Russian Ministry of Health
Email: scvssd@yandex.ru
Professor
V. Polyakova
I.I. Mechnikov North-West State Medical University Russian Ministry of Health
Email: scvssd@yandex.ru
Associate Professor
V. Dobritsa
I.I. Mechnikov North-West State Medical University Russian Ministry of Health
编辑信件的主要联系方式.
Email: scvssd@yandex.ru
Professor
参考
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