GENDER DIFFERENCES IN ARTERIAL RIGIDITY IN SUBJECTS WITH CARDIOVASCULAR DISEASE RISK FACTORS
- 作者: Petleva Y.1, Dokina E.1, Alekseeva L.1
-
隶属关系:
- Polyclinic One, Department for Presidential Affairs of the Russian Federation
- 期: 卷 23, 编号 8 (2012)
- 页面: 62-64
- 栏目: Articles
- URL: https://journals.eco-vector.com/0236-3054/article/view/115479
- ID: 115479
如何引用文章
开放存取
##reader.subscriptionAccessGranted##
详细
The impact of gender on arterial rigidity indices was studied in 134 apparently healthy public officers aged less than 60 years: in 74 men (mean age 48,96±8,53 years) and 60 women 53,95±5,61 years; p<0,05). 75% were in menopause. The groups were comparable in the prevalence of hypertensive disease, average heart rate, levels of cholesterol, low-density lipoproteins, and fasting glucose. The men had significantly higher office blood pressure levels and more frequently overweight and the women were more often recorded to have increased aortic augmentation index and higher aortic pulse wave velocity (APWV). The abnormal APWV rise (>12 m/sec) was observed in 29.58% of the women and in 12,7% of the men (p=0,02), which may be due to the specific features of remodeling of the vascular wall and its altered elastic properties in menopause.
全文:
作者简介
Yu. Petleva
Polyclinic One, Department for Presidential Affairs of the Russian Federation
E. Dokina
Polyclinic One, Department for Presidential Affairs of the Russian Federation
Email: elena.dokina@mail.ru
Candidate of Medical Sciences
L. Alekseeva
Polyclinic One, Department for Presidential Affairs of the Russian FederationProfessor, MD
参考
- Бойцов С.А. Взаимосвязи артериосклероза, атеросклероза и артериальной гипертонии - старый вопрос в свете новых данных // Тер. арх. - 2009; 12: 5-11.
- Новые возможности оценки артериальной ригидности - раннего маркера развития сердечно-сосудистых заболеваний / Материалы симпозиума. Под ред. А.И. Мартынова. - М.: Русский врач. - 2007; 48 с.
- Орлова Я.А., Агеев Ф.Т. Жесткость артерий как интегральный показатель сердечно-сосудистого риска: физиология, методы оценки и медикаментозной коррекции // Сердце. - 2006; 2 (26): 65-9.
- Boutouyrie P., Tropeano A., Asmar R. et al. Aotic stiffness is an independent predictor of primary coronary events in hypertensive patients: a longitudinaj study // Hypertension. - 2002; 39: 10-5.
- Intengan H., Schiffirin E. Structure and mechanical properties of resistance arteries in hypertension: role of adhesion molecules and extracellular matrix determinations // Hypertension. - 2000; 36: 312-8.
- Jolda-Mydlowska B., Kobusiak-Prokopowicz M., Stawuta A. et al. Pulse pressure as a prognostic indicator of organ damage in patients with essential hypertension // Рol. Arch. Med. Wewn. - 2004; 111 (5): 527-35.
- Illyes М. A new and fast screening method for measuring complex hemodynamical parameters and arterial stiffness noninvasively with simple arm cuff // Am. J. Hypertens. - 2005; 18 (5): 17.
- Laurent S., Katsahian S., Fassot C. et al. Aortic stiffness is an independent predictor of fatal stroke in essential hypertension // Stroke. - 2003; 34 (5): 1203-6.
- Laurent S., Boutouyrie P., Lacolley P. Structural and genetic bases of arterial stiffness // Hypertension. - 2005; 45: 1050-5.
- Oliver J., Webb D. Noninvasive assessment of arterial stiffness and risk of atherosclerotic events // Arterioscler. Tromb. Vasc. Biol. - 2003; 23: 554-66.
- Shokawa T., Imazu M., Yamamoto H. et al. Pulse wave velocity predicts cardiovascular mortality: findings from the Hawaii-Los Angeles-Hiroshima study // Circ. J. - 2005; 69: 259-64.
- Takahashi K., Miura S., Mori-Abe A. et al. Impact of menopause on the augmentation of arterial stiffness with aging // Gynecol. Obstet. Invest. - 2005; 60 (3): 162-6.
- Hansen Т., Staessen Y., Torp-Pedersen С. еt al. Prognostic Value of Aortic Pulse Wave Velocity as Index of Arterial Stiffness in the General Population // Circulation. - 2006; 113: 664-70.
- van Bortel L., Struijker-Boudier H., Safar M. Pulse pressure, arterial stiffness and drug treatment of hypertension // Hypertension. - 2001; 38: 914-21.
- Ward M., Pasterkamp G., Yeung A. et al. Arterial remodelling. Mechanism and implications // Circulation. - 2000; 102: 1186-91.
补充文件
