GENDER DIFFERENCES IN ARTERIAL RIGIDITY IN SUBJECTS WITH CARDIOVASCULAR DISEASE RISK FACTORS


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Abstract

The impact of gender on arterial rigidity indices was studied in 134 apparently healthy public officers aged less than 60 years: in 74 men (mean age 48,96±8,53 years) and 60 women 53,95±5,61 years; p<0,05). 75% were in menopause. The groups were comparable in the prevalence of hypertensive disease, average heart rate, levels of cholesterol, low-density lipoproteins, and fasting glucose. The men had significantly higher office blood pressure levels and more frequently overweight and the women were more often recorded to have increased aortic augmentation index and higher aortic pulse wave velocity (APWV). The abnormal APWV rise (>12 m/sec) was observed in 29.58% of the women and in 12,7% of the men (p=0,02), which may be due to the specific features of remodeling of the vascular wall and its altered elastic properties in menopause.

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About the authors

Yu. Petleva

Polyclinic One, Department for Presidential Affairs of the Russian Federation

E. Dokina

Polyclinic One, Department for Presidential Affairs of the Russian Federation

Email: elena.dokina@mail.ru
Candidate of Medical Sciences

L. Alekseeva

Polyclinic One, Department for Presidential Affairs of the Russian Federation

Professor, MD

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