EFFECT OF QUDESAN ON CYTOCHROME P450 3A4: ELECTROCHEMICAL STUDY
- 作者: Shumyantseva V.1, Shikh E.1, Makhova A.1, Bulko T.1, Suprun E.1
-
隶属关系:
- 期: 卷 24, 编号 4 (2013)
- 页面: 40-44
- 栏目: Articles
- URL: https://journals.eco-vector.com/0236-3054/article/view/115683
- ID: 115683
如何引用文章
开放存取
##reader.subscriptionAccessGranted##
详细
Electrochemical analysis has shown that due to its antioxidant effect, Qudesan is able to affect drug metabolism during combination therapy by inducing the activity of cytochrome P450 3A4. It may have widespread use in patients with cardiovascular diseases.
全文:
参考
- Marcoff L., Thompson P. The role of coenzyme Q10 in statin-associated myopathy: a systematic review // J. Am. Coll. Cardiol. - 2007; 49: 2231-7.
- Ланкин В.З., Тихазе А.К., Беленков Ю.Н. Антиоксиданты в комплексной терапии атеросклероза: pro et contra // Кардиология. - 2004; 2: 72-81.
- Каленикова Е.И., Городецкая Е.А., Медведев О.С. Фармакокинетика коэнзима Q10 // РМЖ. - 2008; 16 (5): 338-40.
- Лакомкин В.Л., Коркина О.В. и др. Защитное действие убихинона (коэнзима Q10) при ишемии и реперфузии сердца // Кардиология. - 2002; 12: 51-5.
- Aejmelaeus R., Metsa-Ketela T. et al. Ubiquinol-10 and total peroxil radical trapping capacity of LDL lipoproteins during aging: the effects of Q-10 supplementation // Mol. Aspects Med. - 1997; 18: 113-20.
- Watts G., Castelluccio C., Rice-Evans C. et al. Plasma coenzyme Q10 (ubiquinone) concentrations in patients treated with simvastatin // J. Clin. Pathol. -1993; 46: 1055-7.
- Lewis D. Guide to Cytochrome P450. Structure and function. London and New York, 2001.
- Im S., Waskell L. The interaction of microsomal cytochrome P450 2B4 with its redox partners, cytochrome P450 reductase and cytochrome b5 // Arch. Biochem. Biophys. -2011; 507: 144-53.
- Шумянцева В.В., Ших Е.В., Махова А.А. и др. Влияние витаминов группы В на монооксигеназную активность цитохрома Р450 3А4: фармакокинетические исследования и электроанализ каталитических свойств // Биомед. химия. - 2011; 57 (3): 343-54.
- Makhova A., Shumyantseva V., Shich E. et al. Electroanalysis of Cytochrome P450 3A4 Catalytic Properties with Nanostructured Electrodes: The Influence of Vitamin B Group on Diclofenac Metabolism // Bio. Nano Sci. - 2011; 1: 46-52.
- Fantuzzi A., Mak L., Capria E. et al. A new standardized electrochemical array for drug metabolic profiling with human cytochromes P450 // Anal. Chem. -2011; 83: 3831-9.
- Shumyantseva V., Bulko, T., Suprun E. et al. Electrochemical investigations of cytochrome P450 // Biochem. Biophys. Acta, Proteins and Proteomics. - 2011; 1814: 94-101.
- Jeong J., Kim C., Yoon J. The effect of electrode material on the generation of oxidants and microbial inactivation in the electrochemical disinfection processes // Water research. - 2009; 43: 895-901.
补充文件
