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Vol 24, No 4 (2013)

Articles

NARCOTIC DRUGS IN RUSSIA

Palekhov A.

Abstract

The paper gives data on the use of strong opioids (narcotic drugs) in Russia. It analyzes the main reasons for their insufficient use and defines the basic organizational measures contributing to the higher quality of therapy for chronic pain syndromes.
Vrach. 2013;24(4):2-5
pages 2-5 views

TPIGEMINAL NEURALGIA: EPIDEMIOLOGY, ETIOLOGY, PATHOMORPHOLOGY, PATHOGENESIS, CLINICAL PICTURE, DIAGNOSIS

Manvelov L., Tyurnlkov V., Kadykov A.

Abstract

The paper deals with the epidemiology, etiology, pathomorphology, pathogenesis, clinical picture, and diagnosis of trigeminal neuralgia.
Vrach. 2013;24(4):6-8
pages 6-8 views

ANXIETY DISORDERS AND PREGNANCY

Ushkalova A., Ushkalova E.

Abstract

The paper describes the epidemiology and the course of anxiety disorders during pregnancy, their impact on maternal and fetal outcomes, the specific features of pharmacotherapy, and the potential negative effects of drugs on the fetus/ newborn infant.
Vrach. 2013;24(4):9-12
pages 9-12 views

THE POSITIVE ROLE OF OBESITY IN THE CLINICAL PRESENTATION OF VISCERAL DISEASES

Noskov S., Sherina T., Pryanlchnlkova A.

Abstract

The paper analyzes an update on the impact of obesity on mortality rates in cardiovascular and respiratory diseases and diabetes mellitus. It considers the possible causes of an obesity paradox and puts forth a theory of the particular role of the muscular system.
Vrach. 2013;24(4):13-17
pages 13-17 views

PANANGIN IN THE ARSENAL OF A GENERAL PRACTITIONER

Lebedeva M.

Abstract

The paper presents data on the pathogenesis of imbalance between potassium and magnesium ions and on the methods of its correction.
Vrach. 2013;24(4):17-20
pages 17-20 views

EXTENSION OF THERAPEUTIC POSSIBILITIES IN STABLE CORONARY HEART DISEASE

Khadzegova A.

Abstract

This observation demonstrates an association between heart rate and the occurrence of myocardial ischemia. The paper discusses problems in heart rate-reducing therapy for stable angina pectoris and the advantages of combination therapy with β-adrenoblockers and the If-channel inhibitor Coraxan.
Vrach. 2013;24(4):21-25
pages 21-25 views

EFFECT OF TRIMETAZIDINE ON QT INTERVAL DURATION AND DISPERSION IN PATIENTS WITH PERSISTENT ATRIAL FIBRILLATION

Pavlovskaya E., Avtandllov A., Vertklna N., Pukhaeva A.

Abstract

The effect of trimetazidine on the electric systole of the left ventricle was investigated in patients with coronary heart disease and persistent atrial fibrillation. It is shown that there is significantly reduced QT dispersion when trimetazidine is added to antiarrhythmic therapy.
Vrach. 2013;24(4):25-28
pages 25-28 views

CORRECTION OF COGNITIVE IMPAIRMENTS IN ARTERIAL HYPERTENSION

Sizova Z., Lapldus N., Bogatyreva L.

Abstract

The paper considers possibilities for the pharmacological correction of cognitive disorders in outpatients with arterial hypertension.
Vrach. 2013;24(4):28-31
pages 28-31 views

EFFICACY OF LISINOPRIL IN CHRONIC KIDNEY DISEASE

Moiseev S., Strlzhakov L.

Abstract

The paper considers the results of controlled clinical trials evaluating the efficacy of lisinopril in the prevention of cardiovascular and renal outcomes in patients with arterial hypertension, including those with chronic kidney disease, as well as the nephroprotective properties of the drug in patients with diabetes mellitus and nondiabetic nephropathies.
Vrach. 2013;24(4):32-36
pages 32-36 views

EFFECT OF TRIMETAZIDINE IN A ROSUVASTATIN-BISOPROLOL COMBINATION ON BLOOD LEVELS OF C-REACTIVE PROTEIN AND GLUCOSE IN PATIENTS WITH CORONARY HEART DISEASE

Shevchenko A., Shevchenko O., Khalllyulin T., Pavlov V., Serdyuk O., Peredelkina A.

Abstract

This controlled pilot study showed that just 2 weeks after therapy with bisoprolol and rozuvastatine, the trimetazidine (Predizine)-treated patients with stable angina pectoris without diabetes mellitus had lower blood glucose and C-reactive protein levels and fewer angina attacks and needed less additional use of nitroglycerin and amlodipine.
Vrach. 2013;24(4):36-40
pages 36-40 views

EFFECT OF QUDESAN ON CYTOCHROME P450 3A4: ELECTROCHEMICAL STUDY

Shumyantseva V., Shikh E., Makhova A., Bulko T., Suprun E.

Abstract

Electrochemical analysis has shown that due to its antioxidant effect, Qudesan is able to affect drug metabolism during combination therapy by inducing the activity of cytochrome P450 3A4. It may have widespread use in patients with cardiovascular diseases.
Vrach. 2013;24(4):40-44
pages 40-44 views

VERSATILE CLINICAL USE OF ROSUVASTATIN: SHOULD ITS LIPID-LOWERING PROPERTIES BE RELIED ON?

Ovsyannikov A., Sorokin A.

Abstract

The paper shows both the lipid-lowering and pleiotropic (non-lipid) effects of rosuvastatin and experimental and clinical backgrounds for its use as both mono- and combination therapy in patients with cardiovascular and associated diseases.
Vrach. 2013;24(4):44-47
pages 44-47 views

INTERFERON INDUCER AMIXIN IN THE PREVENTION AND TREATMENT OF ACUTE RESPIRATORY VIRAL INFECTIONS AND INFLUENZA

Selkova E., Volchetsky A., Lapitskaya A.

Abstract

The paper outlines the main advantages of interferon (IFB) inducers and gives data on their efficacy in treating and preventing acute respiratory viral infections. It presents the results of trials evaluating the efficacy of the IFN inducer Amixin.
Vrach. 2013;24(4):48-54
pages 48-54 views

DEVELOPMENT OF COGNITIVE IMPAIRMENTS IN DIABETIC PATIENTS AFTER PREVIOUS ISCHEMIC STROKE

Shlshkova V., Remennik A., Shklovsky V., Fukalov Y.

Abstract

Diabetes mellitus (DM) that has reached epidemic proportions in the past decade serves as one of the major risk factors of stroke, ischemic stroke in particular. The main cause of death in type 2 DM is vascular (including cerebrovascular) complications. Due to cognitive deficit occurring in DM, the patients are a dementia risk group. The use of Noojerone may slow down the progression of neuro-degenerative diseases and accelerate speech recovery.
Vrach. 2013;24(4):55-61
pages 55-61 views

NON-DRUG TREATMENTS FOR CHRONIC VERTEBROBASILAR INSUFFICIENCY

Tyan V.

Abstract

The use of biodynamic correction and reflex therapy in the combination treatment of patients with vertebrobasilar insufficiency leads to neurological regression and increased pain threshold and normalizes cerebral hemodynamic parameters.
Vrach. 2013;24(4):62-65
pages 62-65 views

THERAPY FOR CARDIONEUROSIS (NEUROCIRCULATORY DYSTONIA) IN THE GENERAL MEDICAL NETWORK

Medvedev V., Eplfanov A., Lartseva O.

Abstract

The clinical picture of cardioneurosis is heterogeneous and encompasses the symptoms of anxiety/phobia, senestalgia, and depressive disorders. The prescriptions from general practitioners who most commonly follow up this category of patients are usually limited by recommendations for the use of tranquilizers. The current selective melatoninergic antidepressant Valdoxan has demonstrated high efficacy and good tolerance in patients with cardioneurosis (autonomic vascular dystonia).
Vrach. 2013;24(4):66-71
pages 66-71 views

USE OF FIXED-DOSE DRUG COMBINATION

Ageenkova O.

Abstract

A fixed-dose angiotensin-converting enzyme inhibitor-calcium antagonist combination (Prestans, Servier) demonstrated not only a pronounced antihypertensive effect, but also a favorable organ-protective activity in hypertensive patients.
Vrach. 2013;24(4):72-75
pages 72-75 views

CYTOKINE STATUS IN CORONARY HEART DISEASE PATIENTS WITH METABOLIC SYNDROME AND POSSIBILITIES OF ITS CORRECTION

Dontsov A.

Abstract

Current conventional drug therapy for coronary heart disease (CHD) has no sufficient impact on systemic subclinical inflammation. The results of a trial showing that dalargin and low-intensity laser radiation may lower the elaboration of proinflammatory cytokines in patients with CHD and metabolic syndrome are given.
Vrach. 2013;24(4):76-77
pages 76-77 views

MYOCARDIAL FUNCTIONAL STATUS AND NATRIURETIC PROPEPTIDE LEVELS IN ACROMEGALY AT DIFFERENT DISEASE STAGES

Kosareva O., Sharonova L., Verbovoy A.

Abstract

The paper gives the data of echocardiography and the results of an investigation of natriuretic propeptide levels in 46 patients with acromegaly in its active and remission stages. Analysis has revealed the disadaptative pattern of left ventricular remodeling, diastolic dysfunction, and a significant increase in pro-BNP levels in patients with acromegaly irrespective of disease stage.
Vrach. 2013;24(4):78-81
pages 78-81 views

CYTOLOGICAL STUDY IN THE DIAGNOSIS OF HYPERPARATHYROIDISM

Zakharova N., Vetchinnikova O., Ivantsova L., Vladimirova K.

Abstract

The cytological examination of parathyroid tissue obtained during fine-needle aspiration biopsy under ultrasound guidance is a highly informative method of the topical diagnosis of abnormally altered parathyroids in hyperparathyroidism.
Vrach. 2013;24(4):81-84
pages 81-84 views

KEY RISKS IN THE CREATION OF THE INFORMATION SYSTEM OF MOBILE DIAGNOSTIC UNIT

Denisov I., Sidelnikov K.

Abstract

The results of the study of the risks of the information system of mobile diagnostic device, made as part of the Selection of the concept of mobile diagnostic unit conducted Fund «Skolkovo». Focuses on the challenges of creating a health information system.
Vrach. 2013;24(4):86-88
pages 86-88 views

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