SUSTAINED-RELEASE SYMPTOM-MODIFYING DRUGS FOR KNEE OSTEOARTHROSIS


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The investigation of 70 patients with knee osteoarthrosis and comorbid obesity demonstrated that the functional outcomes of 3-month intake of chondroitin sulfate, diacerein, and zinaxin were comparable.

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参考

  1. Bartels E., Bliddal H., Schendorff P. et al. Symptomatic efficacy and safety of diacerein in the treatment ofosteoarthritis: a meta-analysis of randomized placebo-controlled trials. Osteoarthritis Cartilage. - 2010; 18 (3): 289-96.
  2. Hochberg M., Chevalier X., Henrotin Y. et al. Symptom and structure modification in osteoarthritis with pharmaceutical-grade chondroitin sulfate: what's the evidence? // Curr. Med. Res. Upin. - 2013; 29 (3): 259-67.
  3. Leach M., Kumar S. The clinical effectiveness of Ginger (Zingiber officinale) in adults withosteoarthritis // Int. J Evid. Based Healthc. - 2008; 6 (3): 311-20.
  4. Красивина И.Г., Носкова А.С., Долгова Л.Н. Способ количественного определения мышечной слабости коленных суставов. Патент на изобретение №2289296. Зарегистрировано в Государственном реестре РФ 20.12.2006.
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  6. Ramos-Zavala et al. Effect of diacerein on insulin secretion and metabolic control in drug-naïve patients with type 2 diabetes: a randomized clinical trial // Diabetes Care. - 2011; 34: 1591-4.

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