COMPLICATIONS OF GASTROESOPHAGEAL REFLUX DISEASE IN ELDERLY PATIENTS


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详细

The incidence of complicated gastroesophageal reflux disease is more than 2.5-fold higher in elderly people. The age factor is of the greatest importance for mucosal ulceration in the distal esophagus. The proton pump inhibitor (PPI)-alginate (Gaviscon®) combination is a more pathogenetically sound treatment than PPI monotherapy.

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作者简介

E. Onuchlna

Irkutsk State Medical Academy of Postgraduate Education

Email: elonu@mail.ru

S. Brlkova

War Veterans Hospital

Irkutsk

Yu. Belikova

War Veterans Hospital

Irkutsk

S. Gontarenko

War Veterans Hospital

Irkutsk

参考

  1. Онучина Е.В., Брикова С.И., Цуканов В.В. Использование препарата Гевискон для купирования симптоматики пищеводных, внепищеводных синдромов и функциональной диспепсии у больных ГЭРБ пожилого и старческого возраста // Эксперим. и клин. гастроэнтерол. - 2010; 10: 80-6.
  2. Онучина Е.В. Клинические проявления, факторы риска и эффективность лечения гастроэзофагеальной рефлюксной болезни у лиц пожилого возраста. Автореф. дис..д-ра мед. наук. Красноярск, 2011; с. 45.
  3. Ang, D., Sifrim D., Tack J. Mechanisms of heartburn // Nat. Clin. Pract. Gastroenterol. Hepatol. - 2008; 5: 383-92.
  4. Corley D., Kubo A., Levin T. et al. Race, ethnicity, sex and temporal differences in Barrett's oesophagus diagnosis: a large community-based study, 1994-2006 // Gut. - 2009; 58: 182-8.
  5. Farré R., Fornari F., Blondeau K. et al. Acid and weakly acidic solutions impair mucosal integrity of distal exposed and proximal non-exposed human oesophagus // Gut. - 2010; 59: 164-9.
  6. Kwiatek M., Roman S., Fareeduddin A. et al. An alginate-antacid formulation (Gaviscon Double Action Liquid) can eliminate or displace the postprandial 'acid pocket' in symptomatic GERD patients // Aliment. Pharmacol. Ther. - 2011; 34: 59-66.
  7. Lien H., Chang C., Yeh H. et al. Increasing prevalence of erosive esophagitis among Taiwanese aged 40 years and above: a comparison between two time periods // J. Clin. Gastroenterol. - 2009; 43: 926-32.
  8. Lundell L., Dent J., Bennet J. Endoscopic assessment of oesophagitis clinical and functional correlates and futher validation of Los Angeles classification // Gut. - 1999; 45: 72-180.
  9. Murray L., Watson P., Johnston B. et al. Risk of adenocarcinoma in Barrett's oesophagus: population based study // BMJ. - 2003; 327: 534-5.
  10. Salvioli G., Tambara E., Gaetti E. et al. Chemico-physical property and bile acid binding capacity of several antacids // Minerva Dietol/Gastroenterol. - 1989; 35: 79-83.
  11. Savarino E., de Bortoli N., Zentilin P. et al. Alginate controls hear burn in patients with erosive and nonerosive reflux disease // World J. Gastroenterol. -2012; 18: 4371-8.
  12. Spechler S., Sharma P., Souza R. et al. American Gastroenterological Association technical review on the management of Barrett's esophagus // Gastroenterology. - 2011; 140: 18-52.
  13. Strugala V., Avis J., Jolliffe I.G. et al. The role of an alginate suspension on pepsin and bile acids - key aggressors in the gastric refluxate. Does this have implications for the treatment of gastro-oesophageal reflux disease? // J. Pharm. Pharmacol. - 2009; 61: 1021-8.
  14. Vakil N., van Zanten S., Kahrilas P. et al. The Monreal Definition and Classification of gastroesophageal reflux disease: a global evidence-based consensus // Am. J. Gastroenterology. - 2006; 101: 1900-20.
  15. Zerbib F., Roman S., Ropert A., et al. Esophageal pH-impedance monitoring and symptom analysis in GERD: a study in patients off and on therapy // Am. J. Gastroenterol. - 2006; 101: 1956-63.
  16. Hampson F. et al. Alginate rafts and their characterization // Int. J. Pharm. -2005; 294 (1-2): 137-47.

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