Assotsiatsiya polimorfizma gena CYP2D6 s profilem effektivnosti i bezopasnosti galoperidola pri alkogol'noy zavisimosti


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The study involved 20 men with alcohol addiction. The efficacy and safety of haloperidol was evaluated by international psychometric scales. The genotype of CYP2D6 was investigated by real-time PCR. The study revealed a statistically significant patterns between the polymorphism of CYP2D6 and the efficacy and safety of haloperidol.

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作者简介

M. Zastrozhin

Russian Medical Academy of Postgraduate Education;Peoples’ Friendship University of Russia

Email: rudnmed@yandex.ru

K. Ryzhikova

Russian Medical Academy of Postgraduate Education

Email: rudnmed@yandex.ru

O. Avdeeva

Russian Medical Academy of Postgraduate Education

Email: rudnmed@yandex.ru

J. Sozaeva

Russian Medical Academy of Postgraduate Education

Email: rudnmed@yandex.ru

E. Grishina

Russian Medical Academy of Postgraduate Education

Email: rudnmed@yandex.ru
Candidate of Medical Sciences

D. Sychev

Russian Medical Academy of Postgraduate Education

Email: rudnmed@yandex.ru
Professor

E. Brune

Peoples’ Friendship University of Russia

Email: rudnmed@yandex.ru
Professor

L. Savchenko

Russian Medical Academy of Postgraduate Education

Email: rudnmed@yandex.ru
Candidate of Medical Sciences

N. Sannikova

Moscow Research and Practical Centre for Narcology

Email: rudnmed@yandex.ru

参考

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