13C-METHACETIN BREATH TEST IN GASTROENTEROLOGICAL PRACTICE


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详细

The 13C-methacetin breath test (13C-Meth-BT) is used to diagnose hepatocellular failure, to define the stages of fibrosis, and to monitor their dynamics in chronic liver diseases without using invasive diagnostic tests (liver biopsy). The role of 13C-Meth-BT in diagnosing the functional status of hepatocytes has been defined in liver diseases from various causes.

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作者简介

I. Klyaritskaya

S.I. Georgievsky Medical Academy, V.I. Vernadsky Crimean Federal University Simferopol

E. Stilidi

S.I. Georgievsky Medical Academy, V.I. Vernadsky Crimean Federal University Simferopol

E. Shelikhova

S.I. Georgievsky Medical Academy, V.I. Vernadsky Crimean Federal University Simferopol

E. Maksimova

S.I. Georgievsky Medical Academy, V.I. Vernadsky Crimean Federal University Simferopol

参考

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  2. Petrolati А., Festi D., DeBerardinis G. 13C-methacetine breath test for monitoring hepatic function in cirrotic patients before and after liver transplantation // Aliment. Pharmacol. Ther. - 2003; 18: 785-90.
  3. Frye R. et al. Liver disease selectively modulates cytochrome P450-mediated metabolism. // Clin. Pharmacol. Ther. - 2006; 80: 235-45.
  4. Nista E. et al. 13C-Breath Tests in the study of microsomal liver function // Eur. Rev. Med. Pharmacol. Sci. - 200; 8 (1): 33-46.
  5. Кляритская И.Л., Стилиди Е.И. Патогенетическое значение провоспали-тельных цитокинов в формировании и прогрессировании фиброза при алкогольном гепатите // Эксперим. и клин. гастроэнтерол. - 2013; 4: 13-9.

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