Clinical manifestations of gastroesophageal reflux disease and anxiety in patients with metabolic syndrome

E. V. Shrayner; Шрайнер Е. В.; K. E. Kalashnikova; Калашникова К. Е.; V, I. Bystrova; Быстрова В. И.; D. A. Lukichev; Лукичев Д. А.; I. I. Smirnova; Смирнова И. И.; A. N. Sultanova; Султанова А. Н.; D. A. Kudlay; Кудлай Д. А.

doi:10.29296/25877305-2025-08-14

Clinical manifestations of gastroesophageal reflux disease and anxiety in patients with metabolic syndrome

作者: Shrayner E.V.¹^,2, Kalashnikova K.E.¹, Bystrova V.I.¹^,2, Lukichev D.A.¹, Smirnova I.I.³, Sultanova A.N.³, Kudlay D.A.¹^,4^,5
隶属关系:
1. Novosibirsk State University
2. Institute of Chemical Biology and Fundamental Medicine of Siberian Branch of the Russian Academy of Sciences
3. Novosibirsk State Medical University, Ministry of Health of Russia
4. I.M. Sechenov First Moscow State Medical University, Ministry of Health of Russia (Sechenov University)
5. M.V. Lomonosov Moscow State University
期: 卷 36, 编号 8 (2025)
页面: 71-74
栏目: From Practice
URL: https://journals.eco-vector.com/0236-3054/article/view/689988
DOI: https://doi.org/10.29296/25877305-2025-08-14
ID: 689988

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详细

Metabolic syndrome (MS) is a global medical and social concern that significantly impacts various physiological systems, including the gastrointestinal tract. One of the most common associated pathologies is gastroesophageal reflux disease (GERD). This study aimed to evaluate the severity of clinical manifestations of GERD and anxiety disorders in patients with MS. A comparative analysis was conducted between two groups: patients with combined MS and GERD, and patients with isolated GERD. The study included clinical examination, assessment using the Spielberger State-Trait Anxiety Inventory (STAI), and instrumental diagnostics. The results demonstrated higher levels of anxiety and more severe GERD symptoms in patients with MS. A statistically significant association was revealed between MS and esophageal mucosal injury.

关键词

metabolic syndrome, gastroesophageal reflux disease, anxiety, obesity, esophagitis

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作者简介

E. Shrayner

Novosibirsk State University; Institute of Chemical Biology and Fundamental Medicine of Siberian Branch of the Russian Academy of Sciences

编辑信件的主要联系方式.
Email: sch704@icloud.com
ORCID iD: 0000-0003-3606-4068
SPIN 代码: 1089-6080

Candidate of Medical Sciences

俄罗斯联邦, Novosibirsk; Novosibirsk

俄罗斯联邦, Novosibirsk

D. Kudlay

Novosibirsk State University; I.M. Sechenov First Moscow State Medical University, Ministry of Health of Russia (Sechenov University); M.V. Lomonosov Moscow State University

Email: sch704@icloud.com
ORCID iD: 0000-0003-1878-4467
SPIN 代码: 4129-7880

Professor, Corresponding Member of the Russian Academy of Sciences, MD

俄罗斯联邦, Novosibirsk; Moscow; Moscow

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