New approaches to natural fertility recovery in the polycystic ovary syndrome and their impact on the therapeutic potential of in-vitro fertilization


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Objective: to study the impact of uni- and bilateral interventions into the ovaries in infertile patients with polycystic ovary syndrome (PCOS) in order to achieve natural fertility and in the in-vitro fertilization (IVF) programs. Setting: Moscow Regional Research Institute of Obstetrics and Gynecology; Central Hospital, Medical Center of the Special Construction Committee of Russia. Design: a prospective comparative study. Subjects: 109 patients with infertility caused by PCOS. Methods: clinical and laboratory studies. Results: in patients with PCOS, an operation on one ovary yields the results comparable with bilateral intervention in criteria for ovulation recovery and spontaneous pregnancy achievement. The use of an IVF procedure showed worse treatment results in PCOS patients who had undergone bilateral ovarian surgery than in those who had been operated on one ovary. Conclusion: It has been established that it is expedient to use unilateral ovarian interventions in the surgical treatment in PCOS patients, the main aim of which is to eliminate infertility.

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