Physiological bases of regulation of uterine contractility


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Abstract

The review discusses the maintenance of myometrial quiescence during pregnancy and the sequence of events contributing to the development of powerful rhythmic contractile uterine activity during labor. The mechanisms of electromechanical coupling in uterine cells and the role of the sarcoplasmic reticulum in the kinetics of intracellular calcium regulation during contraction and relaxation of myometrial cells are considered in detail. Coordination of the interaction between the corpus and cervix uteri is discussed.

About the authors

Vladislav Viktorovich Kovalev

Email: omm@k66. ru

P B Tsyv'yan

N M Milyaeva

O N Lukin

Yu L Protsenko

V V Kovalev

Urals Research Institute of Maternity and Infancy Care, Russian Agency for Medical Technology

Urals Research Institute of Maternity and Infancy Care, Russian Agency for Medical Technology

P B Tsyvyan

Urals Research Institute of Maternity and Infancy Care, Russian Agency for Medical Technology

Urals Research Institute of Maternity and Infancy Care, Russian Agency for Medical Technology

N M Milyaeva

Urals Research Institute of Maternity and Infancy Care, Russian Agency for Medical Technology

Urals Research Institute of Maternity and Infancy Care, Russian Agency for Medical Technology

O N Lukin

Urals Research Institute of Maternity and Infancy Care, Russian Agency for Medical Technology

Urals Research Institute of Maternity and Infancy Care, Russian Agency for Medical Technology

Yu L Protsenko

Institute of Immunology and Physiology, Urals Branch, Russian Academy of Sciences, Yekaterinburg

Institute of Immunology and Physiology, Urals Branch, Russian Academy of Sciences, Yekaterinburg

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