Connective tissue gene polymorphism in stress-induced urinary incontinence in women


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Abstract

The paper reviews the Russian and foreign literature on stress-induced female urinary incontinence and an association of this pathology with connective tissue dysplasia. It outlines different aspects of connective tissue structural impairments that are directly related to the development of urinary incontinence. The impact of polymorphism of genes in connective tissue and a change in their expression on the development of stress-induced urinary incontinence are considered. Determination of gene polymorphism in women with stress-induced urinary incontinence will favor the timely identification of its risk group and its adequate prevention in young women, which is particularly important in pregnant women who have risk factors for stress-induced postpartum urinary incontinence.

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