New approaches to enhancing THE EFFICIENCY OF in vitro fertilization in old reproductive age women


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Abstract

The study was conducted in 40 women with normal total testosterone levels, in 23 patients with low testosterone levels, receiving an androgen-containing agent, and in 28 similar patients taking no drug. In the group of late reproductive age women with lowered androgen-secreting ovarian function, who received no testosterone-containing drug, the rate of a poor response was significantly higher and that of embryo transfer-induced pregnancy was significantly lower than those in the control group. The use of a testosterone preparation could improve the results of in vitro fertilization (IVF) by these criteria. Thus, diminished androgen-secreting ovarian function worsens the efficiency of IVF. The use of a testosterone-containing drug during gonadotropin stimulation improves the results of treatment.

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