Treatment of nongonococcal genital lesions in women
- 作者: Khlybova S.V.1, Reva NL1, Khlybova SV1, Reva NL1
-
隶属关系:
- 期: 编号 2 (2010)
- 页面: 59-63
- 栏目: Articles
- URL: https://journals.eco-vector.com/0300-9092/article/view/246387
- ID: 246387
如何引用文章
全文:
详细
A study was conducted in 49 women with chronic cervicitis and/or complicated by ectopy of the cervix uteri, associated with Chlamydia trachomatis, Mycoplasma genitalium, and Ureaplasma urealyticum, including in combinations with fungi of the genus Candida and the anaerobic microflora. Group 1 included 23 women receiving azithromycin (in a 1-g single dose) in combination with metronidazole (500 mg thrice daily for 7 days) and fluconazole (in a 150-mg single dose). Group 2 comprised 26 women taking Safocid (as a 4-tablet blister per course).
Both drug therapy regimens demonstrated a high clinical efficacy, positive cervical colposcopic changes, and equal antimicrobial activity against C. trachomatis and M. genitalium. Safocid proved to be more effective in eliminating Gardnerella vaginalis in women having microbial associations. At the same time none of the treatment regimens was sufficiently ineffective in eradicating U. urealyticum and Mycoplasma hominis. Safocid showed a good tolerability and a high compliance.
Both drug therapy regimens demonstrated a high clinical efficacy, positive cervical colposcopic changes, and equal antimicrobial activity against C. trachomatis and M. genitalium. Safocid proved to be more effective in eliminating Gardnerella vaginalis in women having microbial associations. At the same time none of the treatment regimens was sufficiently ineffective in eradicating U. urealyticum and Mycoplasma hominis. Safocid showed a good tolerability and a high compliance.
参考
- Бадретдинова Ф. Ф., Ящук Я. Г., Ахматгалиева А. А. и др. // Материалы регионального форума "Мать и дитя". - Казань, 2007. - С. 201.
- Баткаев Э. А. // Вестн. последиплом. мед. образования. - 2003. - № 5. - С. 1-9.
- Белоусов Ю. Б., Карпов О. И., Белоусов Д. Ю. и др. // Качеств. клин. практика. - 2006. - № 3. - С. 1-11.
- Богуш П. Г., Скрипкин Ю. К. // Клин. дерматол. и венерол. - 2005. - № 3. - С. 1-5.
- Европейские стандарты диагностики и лечения заболеваний, передаваемых половым путем: Пер. с англ. под ред. В. П. Адаскевича. - М., 2003.
- Кира Е. Ф. // Гинекология. - 2007. - Экстравып. - С. 9-12.
- Кисина В. И., Прилепская В. Н., Соколовский Е. и др. // Врач. - 2007. - № 2. - С. 1-4.
- Мирзабалаева А. К. // Гинекология. - 2006. - Экстравып. - С. 10-14.
- Серов В. Н., Баранов И. И. // Рус. мед. журн. - 2005. - Т. 13, № 1. - С. 32-34.
- Тихомиров А. Л., Сарсания С. И. // Гинекология. - 2004. - № 6. - С. 10-12.
- Bradshaw C. et al. // Emerg. Infect. Dis. - 2006. - Vol. 12, N 7. - P. 1149-1150.
- Huang C., Liu Z., Lin N. et al. // J. Huazhong Univ. Sci. Technol. Med. Sci. - 2003. - Vol. 23, N 2. - P. 203-205.
- Petitta A., Hart S., Bailey E. // Pharmacotherapy. - 1999. - Vol. 19. - P. 648-654.
- Rose S., Lawton B., Bromhead C. et al. // Hybridoma. - 2007. - Vol. 26, N 5. - P. 333-337.
- Ross O., Jensen O. // Sex. Transm. Infect. - 2006. - Vol. 82, N 4. - P. 269-271.
补充文件
