Efficiency of therapies for bacterial vaginosis in nonpregnant women (results of a multicenter study)


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Abstract

The authors give the results of a multicenter study of the treatment of bacterial vaginosis (BV) in nonpregnant women of reproductive age. They have evaluated the clinical and microbiological efficiency of the diagnosis and treatment of BV in 2505 patients from 14 cities and towns of Russia, by using the unified procedure. The combined treatment for BV with oral trichopol in a dose of 250 mg twice daily for 5 days and intravaginal clindamycin cream on days 1 to 3 of trichopol use have been found to be highly effective (clinical and bacteriological effectiveness being 87.3 and 97.4%), by causing adverse reactions in a few cases (4.1%). Candida vaginitis as a treatment complication was detected in 0.8-1.2% of the women. This treatment regimen for BV is recommended for clinical practice.

About the authors

Ye V Uvarova

Academician V. I. Kulakov Research Center of Obstetrics, Gynecology, and Perinatology, Russian Agency for Medical Technologies, Moscow

Email: uvarova@yandex.ru
Academician V. I. Kulakov Research Center of Obstetrics, Gynecology, and Perinatology, Russian Agency for Medical Technologies, Moscow

A S Ankirskaya

Academician V. I. Kulakov Research Center of Obstetrics, Gynecology, and Perinatology, Russian Agency for Medical Technologies, Moscow

Academician V. I. Kulakov Research Center of Obstetrics, Gynecology, and Perinatology, Russian Agency for Medical Technologies, Moscow

Yu P Grigorenko

Academician V. I. Kulakov Research Center of Obstetrics, Gynecology, and Perinatology, Russian Agency for Medical Technologies, Moscow

Academician V. I. Kulakov Research Center of Obstetrics, Gynecology, and Perinatology, Russian Agency for Medical Technologies, Moscow

Z Kh Kumykova

Academician V. I. Kulakov Research Center of Obstetrics, Gynecology, and Perinatology, Russian Agency for Medical Technologies, Moscow

Academician V. I. Kulakov Research Center of Obstetrics, Gynecology, and Perinatology, Russian Agency for Medical Technologies, Moscow

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