Serum activity of the matrix metalloproteinases MMP-2 and MMP-9 in perimenopausal patients with endometrial hyperplasia


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Abstract

The serum activity of the matrix metalloproteinases (MMP) 2 and 9 was determined in 60 patients with endometrial hyperplasia and in 10 healthy women. In the study group, about a half the female patients were found to have an increase in MMP-2 and MMP-9 activities up to 2+ and 3+. In all healthy women, the activity of MMP was 1+.

About the authors

N V Strizhova

Russian State Medical University

Email: rsmu@rsmu.ru
Russian State Medical University

G M Soboleva

Academician V. I. Kulakov Research Center of Obstetrics, Gynecology, and Perinatology, Russian Agency for Medical Technologies, Moscow

Academician V. I. Kulakov Research Center of Obstetrics, Gynecology, and Perinatology, Russian Agency for Medical Technologies, Moscow

A I Ibragimov

Russian State Medical University

Email: rsmu@rsmu.ru
Russian State Medical University

Ye A Reisner

Russian State Medical University

Email: rsmu@rsmu.ru
Russian State Medical University

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