FETOPLACENTAL ANGIOGENESIS DURING NORMAL PREGNANCY: A ROLE OF VASCULAR ENDOTHELIAL GROWTH FACTOR


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Abstract

The paper gives the data available in the literature on fetoplacental angiogenesis during normal pregnancy. The processes of placental villous vascularization in different periods of pregnancy are considered in detail. The role of vascular endothelial growth factor and its receptors in placental angiogenesis and vasculogenesis is followed. It is shown that there may be adequate angiogenesis and vasculogenesis in the placenta if the interaction of angiogenic factors is balanced.

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About the authors

K. A. PAVLOV

Academician V. I. Kulakov Research Center of Obstetrics, Gynecology, and Perinatology, Ministry of Health and Social Development of Russia

Email: pavlovkos@gmail.com

E. A. DUBOVA

Academician V. I. Kulakov Research Center of Obstetrics, Gynecology, and Perinatology, Ministry of Health and Social Development of Russia

A. I. SHCHEGOLEV

Academician V. I. Kulakov Research Center of Obstetrics, Gynecology, and Perinatology, Ministry of Health and Social Development of Russia

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