OPTIMIZATION OF ANTIRESORPTIVE THERAPY WITH BISPHOSPHONATES


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Abstract

One third of a woman’s life is postmenopausal, i.e. the time of accelerated bone loss, which results in a considerable reduction in bone mineral density and an increase in bone fragility. The first-line drugs for therapy for postmenopausal osteoporosis (PMO) are bisphosphonates (graded validity A). The mean duration of the therapy for PMO is 3 to 5 years. The major problem in treating this disease is low therapy adherence. The design of drugs with the least administrations shows promise for enhancing the adherence to PMO therapy and its effectiveness.

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About the authors

S. V YURENEVA

Academician V. I. Kulakov Research Center of Obstetrics, Gynecology, and Perinatology, Ministry of Health and Social Development of Russia

Email: yurenevas@mail.ru

O. V YAKUSHEVSKAYA

Academician V. I. Kulakov Research Center of Obstetrics, Gynecology, and Perinatology, Ministry of Health and Social Development of Russia

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