POSSIBILITIES FOR PREDICTION OF PREECLAMPSIA


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Abstract

The paper presents data on the possibilities for early prediction of preeclampsia (PE). It considers the parameters reflecting the characteristics of hemodynamics and impaired vascular resistance, endocrine dysfunction of the fetoplacental unit, and renal dysfunction, and those characterizing endothelial dysfunction and oxidative stress. Analysis of the results of the performed studies dealing with the prediction of PE indicates that Doppler study, angiogenic and fetoplacental unit dysfunction factors hold the greatest promise for its early prediction.

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About the authors

T. K GREBENNIK

Academician V. I. Kulakov Research Center of Obstetrics, Gynecology, and Perinatology, Ministry of Health and Social Development of Russia; I.M. Sechenov First Moscow State Medical University

Email: t_grebennik@oparina4.ru

S. V PAVLOVICH

Academician V. I. Kulakov Research Center of Obstetrics, Gynecology, and Perinatology, Ministry of Health and Social Development of Russia; I.M. Sechenov First Moscow State Medical University

References

  1. Мурашко Л.Е., Губарева М.С., Бадоева З.Т. и др. Суточный мониторинг артериального давления при беременности и гестозе // Акуш. и гин. — 2008. — № 3. — С. 61—67.
  2. Пренатальная диагностика наследственных и врожденных болезней / Под ред. Э.К. Айламазяна, В.С. Баранова. — М.: МЕДпресс-информ, 2006.
  3. Преэклампсия / Под ред. Г.Т. Сухих, Л.Е. Мурашко. — М.: ГОЭТАР-Медиа, 2010.
  4. Сухих Г.Т., Вихляева Е.М., Ванько Л.В. и др. Эндотелиальная дисфункция в генезе перинатальной патологии // Акуш. и гин. — 2008. — № 5. — С. 3—7.
  5. Шифман Е.М. Преэклампсия, эклампсия, HELLP-синдром. — Петрозаводск: «ИнтелТек», 2003.
  6. Akolekar R., Minekawa R., Veduta A. et al. Maternal plasma inhibin A at 11-13 weeks of gestation in hypertensive disorders of pregnancy // Prenat. Diagn. — 2009. — Vol. 29, № 8. — P. 753—760.
  7. Anim-Nyame N., Hills F.A., Sooranna S.R. et al. A longitudinal study of maternal plasma insulin-like growth factor binding protein-1 concentrations during normal pregnancy and pregnancies complicated by pre-eclampsia // Hum. Reprod. — 2000. — Vol. 15. — P. 2215—2219.
  8. Ay E., KavakZ.N., Elter K. et al. Screening for pre-eclampsia by using maternal serum inhibin A, activin A, human chorionic gonadotropin, unconjugated estriol, and alpha-fetoprotein levels and uterine artery Doppler in the second trimester of pregnancy // Aust. N. Z. J. Obstet. Gynaecol. — 2005. — Vol. 45. — P. 283—288.
  9. Chafetz I, Kuhnreich I., Sammar M. et al. First-trimester placental protein 13 screening for preeclampsia and intrauterine growth restriction // Am. J. Obstet. Gynecol. — 2007. — Vol. 197. — P. 35—37.
  10. Chavarria M.E., Lara-Gonzàlez L., Gonzàlez-Gleason A. et al. Prostacyclin/thromboxane early changes in pregnancies that are complicated by preeclampsia // Am. J. Obstet. Gynecol. — 2003. — Vol. 188, № 4. — P. 986—992.
  11. Chavarria M.E., Lara-Gonzalez L., Garcia-Paleta Y. et al. Adhesion molecules changes at 20 gestation weeks in pregnancies complicated by preeclampsia // Eur. J. Obstet. Gynecol. Reprod. Biol. — 2008. — Vol. 137. — P. 157—164.
  12. Chien P.F., Arnott N., Gordon A. et al. How useful is uterine artery Doppler flow velocimetry in the prediction of preeclampsia, intrauterine growth retardation and perinatal death? An overview // Br. J. Obstet. Gynaecol. — 2000. — Vol. 107. — P. 196—208.
  13. Cnossen J.S., de Ruyter-Hanhijärvi H., van der Post J.A. et al. Accuracy of serum uric acid determination in predicting pre-eclampsia: a systematic review // Acta Obstet. Gynecol. Scand. — 2006. — Vol. 85, № 5. — P. 519—525.
  14. Cnossen J.S., Morris R.K., ter Riet G. et al. Use of uterine artery Doppler ultrasonography to predict pre-eclampsia and intrauterine growth restriction: a systematic review and bivariable meta-analysis // Can. Med. Assec. J. — 2008. — Vol. 178, № 6. — P. 701—711.
  15. Cnossen J.S., Vollebregt K.C., de Vrieze N. et al. Accuracy of mean arterial pressure and blood pressure measurements in predicting pre-eclampsia: systematic review and metaanalysis// Br. Med. J. — 2008. — Vol. 336. — P. 1117—1120.
  16. Conde-Agudelo A., Romero R., Lindheimer M.D. Tests to predict preeclampsia in chesley’s hypertensive disorders in pregnancy. — 3-rd. ed. — New York: Academic Press, 2009. — P. 189—211.
  17. Dugoff L., Hobbins J.C., Malone F.D. et al. First-trimester maternal serum PAPP-A and free-beta subunit human chorionic gonadotropin concentrations and nuchal translucency are associated with obstetric complications: a population-based screening study (the FASTER Trial) // Am. J. Obstet. Gynecol. — 2004. — Vol. 191. — P. 1446—1451.
  18. Dugoff L., Hobbins J.C. et al. Quad screen as a predictor of adverse pregnancy outcome // Obstet. and Gynecol. — 2005. — Vol. 106, № 2. — P. 260 —267.
  19. Gonen R., Shahar R., Grimpel Y.I. et al. Placental protein 13 as an early marker for pre-eclampsia: a prospective longitudinal study // Br. J. Obstet. Gynaecol. — 2008. — Vol. 115. — P. 1465—1472.
  20. Hunter A., Aitkenhead M., Caldwell C. et al. Serum levels of vascular endothelial growth factor in preeclamptic and normotensive pregnancy // Hypertension. — 2000. — Vol. 36, № 6. — P. 965—969.
  21. Kang J.H., Farina A., Park J.H. et al. Down syndrome biochemical markers and screening for preeclampsia at first and second trimester: correlation with the week of onset and the severity // Prenat. Diagn. — 2008. — Vol. 28. — P. 704—709.
  22. Kyle P.M., Campbell S., Buckley D. et al. A comparison of the inactive urinary kallikrein: creatinine ratio and the angiotensin sensitivity test for the prediction of preeclampsia // Br. J. Obstet. Gynaecol. — 1996. — Vol. 103. — P. 981—987.
  23. Lam C., Lim K.H., Karumanchi S.A. et al. Circulating angiogenic factors in the pathogenesis and prediction of preeclampsia // Hypertension. — 2005. — Vol. 46. — P. 1077—1085.
  24. Lambert-Messerlian G.M., Silver H.M., Petraglia F. et al. Second-trimester levels of maternal serum human chorionic gonadotropin and inhibin a as predictors of preeclampsia in the third trimester of pregnancy // J. Soc. Gynecol. Invest. — 2000. — Vol. 7, № 3. — Р. 170—174.
  25. Lara Gonzàlez A.L., Martinez Jaimes A., Romero Arauz J.F. et al. Microalbuminuria: early prognostic factor ofpreeclampsia? // Ginecol. Obstet. Mex. — 2003. — Vol. 71. — P. 82—86.
  26. Leeflang M.M., Cnossen J.S., van der Post J.A. et al. Accuracy of fibronectin tests for the prediction of pre-eclampsia: a systematic review // Eur. J. Obstet. Gynecol. Reprod. Biol. — 2007. — Vol. 133, № 1. — P. 12—19.
  27. Lepage N., Chitayat D., Kingdom J. et al. Association between second-trimester isolated high maternal serum human chorionic gonadotropin levels and obstetric complications in singleton and twin pregnancies // Am. J. Obstet. Gynecol. — 2003. — Vol. 188. — P. 1354—1359.
  28. Martinez-Abundis E., Gonzalez-Ortiz M., Pascoe-Gonzalez S. et al. Serum leptin levels and the severity of preeclampsia // Arch. Gynecol. Obstet. — 2000. — Vol. 264. — P. 71—73.
  29. Mignini L.E., Latthe P.M., Villar J. et al. Mapping the theories of preeclampsia: the role of homocysteine // Obstet. and Gynecol. — 2005. — Vol. 105. — P. 411—425.
  30. Millar J.G., Campbell S.K., Albano J.D. et al. Early prediction of pre-eclampsia by measurement of kallikrein and creatinine on a random urine sample // Br. J. Obstet. Gynaecol. — 1996. — Vol. 103. — P. 421—426.
  31. Nicolaides K.H., Bindra R., Turan O.M. et al. A novel approach to first-trimester screening for early pre-eclampsia combining serum PP-13 and Doppler ultrasound // Ultrasound Obstet. Gynecol. — 2006. — Vol. 27. — P. 13—17.
  32. Ong C.Y., Liao A.W., Spencer K. et al. First trimester maternal serum free beta human chorionic gonadotrophin and pregnancy associated plasma protein A as predictors of pregnancy complications // Br. J. Obstet. Gynaecol. — 2000. — Vol. 107. — P. 1265—1270.
  33. Parra-Cordero M., Turan O.M., Kaur A. et al. Maternal serum soluble adhesion molecule levels at 11+0-13+6 weeks and subsequent development of pre-eclampsia // J. Matern. Fetal Neonatal Med. — 2007. — Vol. 20. — P. 793—796.
  34. Pilalis A., Souka A.P., Antsaklis P. et al. Screening for preeclampsia and fetal growth restriction by uterine artery Doppler and PAPP-A at 11-14 weeks’ gestation // Ultrasound Obstet. Gynecol. — 2007. — Vol. 29, № 2. — P. 135—140.
  35. Roberts J.M., Pearson G., Cutler J. et al. Summary of the NHLBI working group on research on hypertension during pregnancy // Hypertension. — 2003. — Vol. 41. — P. 437—445.
  36. Rodie V.A., Freeman D.J., Sattar N. et al. Pre-eclampsia and cardiovascular disease: metabolic syndrome of pregnancy // Atherosclerosis. — 2004. — Vol. 175, № 2. — P. 189—202.
  37. Romero R., Kusanovic J.P., Than N.G. et al. First-trimester maternal serum PP13 in the risk assessment for preeclampsia // Am. J. Obstet. Gynecol. — 2008. — Vol. 199. — P. 122. e1—122.e11.
  38. Salako B.L., Odukogbe A.T., Olayemi O. et al. Serum albumin, creatinine, uric acid and hypertensive disorders of pregnancy // East Afr. Med. J. — 2003. — Vol. 80. — P. 424—428.
  39. Sayin N.C., Canda M.T., Ahmet N. et al. The association of triple-marker test results with adverse pregnancy outcomes in low-risk pregnancies with healthy newborns // Arch. Gynecol. Obstet. — 2008. — Vol. 277. — P. 47—53.
  40. Shaarawy M., Salem M.E. The clinical value of microtransferrinuria and microalbuminuria in the prediction of pre-eclampsia // Clin. Chem. Lab. Med. — 2001. — Vol. 39, № 1. — P. 29—34.
  41. Shenhav S., Gemer O., Sassoon E. et al. Midtrimester triple test levels in early and late onset severe pre-eclampsia // Prenat. Diagn. — 2002. — Vol. 22. — P. 579—582.
  42. Shenhav S., Gemer O., Volodarsky M. et al. Midtrimester triple test levels in women with severe preeclampsia and HELLP syndrome // Acta Obstet. Gynecol. Scand. — 2003. — Vol. 82, № 10. — P. 912—915.
  43. Spencer K., Yu C.K.H., Cowans N.J. et al. Prediction ofpregnancy complications by first-trimester maternal serum PAPP-A and free hCG and with second-trimester uterine artery Doppler // Prenat. Diagn. — 2005. — Vol. 25. — P. 949—953.
  44. Spencer K., Cowans N.J., Chefetz I. et al. First-trimester maternal serum PP-13, PAPP-A and second-trimester uterine artery Doppler pulsatility index as markers of preeclampsia // Ultrasound Obstet. Gynecol. — 2007. — Vol. 29. — P. 128—134.
  45. Spencer K., Cowans N.J., Stamatopoulou A. et al. ADAM12s in maternal serum as a potential marker of pre-eclampsia // Prenat. Diagn. — 2008. — Vol. 28. —P. 212—216.
  46. Wald N.J., Morris J.K., Ibison J. et al. Screening in early pregnancy for pre-eclampsia using down syndrome quadruple test markers // Prenat. Diagn. — 2006. — Vol. 26. — P. 559— 564.
  47. Wolf M., Sandler L., Munoz K. et al. First trimester insulin resistance and subsequent preeclampsia: a prospective study // J. Clin. Endocrinol. Metab. — 2002. — Vol. 87. — P. 1563—1568.

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