CURRENT APPROACHES TO IMMUNOPROPHYLAXIS AND TREATMENT OF UNCOMPLICATED URINARY TRACT INFECTIONS IN WOMEN


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Abstract

Urinary tract infections (UTIs) are one of the topical urogynecological problems due to their high prevalence and frequent recurrences and affect not only female physical health, emotional sphere, but also the quality of life as a whole. Uncomplicated UTIs are characterized by recurrences that are generally associated with reinfection in 90% of cases. The groundlessness and irrationality of antibacterial therapy are factors leading to infection chronization and impaired immunoregulatory processes. The alternative approach to treating UTIs is to stimulate intrinsic immune mechanisms against the pathogenic flora, by applying oral immunotherapeutic agents, one of which is a freeze-dried protein extract obtained by fractionation of the alkaline hydrolysate of 18 E. coli strains. The possibilities of phytotherapy using a dry cranberry (Oxycoccus) extract are also of interest now.

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About the authors

I. A APOLIKHINA

Academician V.I. Kulakov Research Center of Obstetrics, Gynecology, and Perinatology, Ministry of Health and Social Development of Russia; I.M. Sechenov First Moscow State Medical University

Email: apolikhina@inbox.ru

T. A TETERINA

I.M. Sechenov First Moscow State Medical University

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