REDUCTION IN THE RISK OF INFECTIOUS COMPLICATIONS DURING ARTIFICIAL PREGNANCY TERMINATION AND THE POSSIBILITIES OF FURTHER REHABILITATION

Objective. To define whether antiseptics (fluomizin) may be used for the reduction of the frequency of postabortion complications and for further rehabilitation and to provide evidence that the lactobacteria- and estriol-containing drug gynoflor E should be given to restore normal vaginal biocenosis in the postabortion period. Subjects and methods. The study covered 100 women (mean age 28.9±0.4 years) who had sought medical advice for artificial pregnancy termination (APT) at 5 to 9 weeks’ gestation. At the first stage of the study after having been examined for vaginal biocenosis, 31 patients diagnosed as having bacterial vaginosis and nonspecif ic vulvovaginitis underwent vaginal sanitation with f luomizin for 6 days prior to APT. At the second stage the women who had used fluomizin to be prepared for APT were given gynoflor E for 6 days after APT (regardless of the used technology) to restore normal vaginal biocenosis. All the pregnant women underwent a conventional clinical and laboratory study involving microscopic examination of vaginal discharge and an additional study of vaginal biocenosis by real-time PCR. Results. The paper gives the results of treatment for nonspecific bacterial vaginal infections, by using a two-step treatment regimen in the pre- and postoperative management of patients during APT. The broad-spectrum drug fluomizin (dequalinium chloride) was found to be effective in treating nonspecific bacterial vaginal infections. Evidence was provided that gynoflor E containing lactobacteria and estriol should be used to restore normal vaginal biocenosis in the postabortion period.

artificial pregnancy termination, vaginal ecosystem, lactobacteria, bacterial vaginosis, nonspecific vulvovaginitis