BIOACTIVE COMPONENTS OF PLANTS AND TREATMENT FOR MENOPAUSAL SYNDROME


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Abstract

The investigation was undertaken to evaluate the eff icacy, tolerability, and safety of soya isoflavonoids for the treatment of the vasomotor, emotional, and autonomic manifestations of the menopausal syndrome (MS), by studying the effect of isoflavones on the blood lipid spectrum. Forty women with MS were given the preparation containing 40 mg of soya isoflavones twice daily for 3 months. The efficacy of the drug was 62.5 and 85% according to diaries and subjective patient assessments, respectively, in the absence of serious adverse reactions. Analysis of the serum lipid spectrum indicated a decline in the levels of cholesterol and low-density lipoproteins, an increase in high-density lipoproteins, and a slight reduction in the atherogenicity index. Thus, soya isoflavonoids are effective, acceptable, and safe medicines to treat MS.

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About the authors

V. N PRILEPSKAYA

Academician V.I. Kulakov Research Center of Obstetrics, Gynecology, and Perinatology, Ministry of Health and Social Development of Russia

A. V LEDINA

Academician V.I. Kulakov Research Center of Obstetrics, Gynecology, and Perinatology, Ministry of Health and Social Development of Russia

Email: ledina2003@mail.ru

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