DESTRUCTION BY FOCUSED ULTRASOUND UNDER GUIDANCE OF MAGNETIC RESONANCE IMAGING AS THE FIRST STAGE OF COMBINATION TREATMENT FOR SUBMUCOUS UTERINE MYOMAS
- Authors: KURASHVILI Y.B1, BARANOV I.I1, KANAYEVA E.Y.2, BATARSHINA O.I1
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Affiliations:
- Academician V.I. Kulakov Research Center of Obstetrics, Gynecology, and Perinatology, Ministry of Health and Social Development of Russia
- Reproductive Medicine Clinic
- Issue: No 4-1 (2012)
- Pages: 70-73
- Section: Articles
- URL: https://journals.eco-vector.com/0300-9092/article/view/246742
- ID: 246742
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Abstract
Objective. To study whether destruction by focused ultrasound (FU) under guidance of magnetic resonance imaging (FUMRI) may be used as a preoperative stage of surgical treatment for submucous uterine myoma. Subjects and methods. In 20 reproductive- and late reproductive-age patients, submucous uterine myoma was preoperatively prepared by FU MRI. Nodules were 3 to 6 cm in diameter. Results. Due to FU destruction, nodular regression was 20 to 60%. All the patients satisfactorily experienced the procedure and called it comfortable. Typical transcervical myomectomy without complications was carried out 3—4 months after FU MRI. Conclusion. FU MRI-guided ablation may serve as the method of choice for the preparation of 3—7-cm submucal nodules for transcervical myomectomy since it is an effective method to reduce nodular volume and an outpatient noninvasive procedure that has no clinically significant systemic effect on the body and that requires no rehabilitation or temporary disability.
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About the authors
Yu. B KURASHVILI
Academician V.I. Kulakov Research Center of Obstetrics, Gynecology, and Perinatology, Ministry of Health and Social Development of RussiaMoscow
I. I BARANOV
Academician V.I. Kulakov Research Center of Obstetrics, Gynecology, and Perinatology, Ministry of Health and Social Development of RussiaMoscow
E. Yu KANAYEVA
Reproductive Medicine ClinicChelyabinsk
O. I BATARSHINA
Academician V.I. Kulakov Research Center of Obstetrics, Gynecology, and Perinatology, Ministry of Health and Social Development of Russia
Email: kira_41@mail.ru
Moscow
References
- Курашвили Ю.Б., Козловская С.Л., Назаренко Т.А., Дубницкая Л.В. Возможности реализации репродуктивной функции у пациенток с миомой матки после МРТкФУЗ (данные литературы, собственный опыт) // Вестн. РУДН. Сер.: «Медицина». - 2009. - № 6.
- Курашвили Ю.Б., Лядов К.В., Коган Е.А. Неинвазивная хирургия миом матки // Журн. акуш. и жен. бол. -2009. - Т. 58, вып. 5. - С. 115-116.
- Лядов К.В., Курашвили Ю.Б., Сидорова И.С. МРТкФУЗа в лечении миомы матки. Руководство для врачей // Здоровье женщины. - 2008.- № 4 (36). - С. 49-64.
- Максутова Д.Ж., Самойлова Т.Е., Коков Л.С. и др. Сравнительная клиническая эффективность и безопасность фокусированной ультразвуковой аблации и эмболизации маточных артерий при лейомиоме матки // Рос. вестн. акуш.-гин. - 2008. - № 2. - С. 44-49.
- Стрижаков А.Н., Коваленко М.В., Давыдов А.И. и др. Лечение миомы матки с помощью фокусированного ультразвукового воздействия под контролем МРТ // Материалы IX Всероссийского научного форума «Мать и дитя». - Москва, 2-5 октября, 2007. - М., 2007. -С. 526.
- Сухих Г.Т., Самойлова Т.Е., Максутова Д.Ж. и др. Опыт применения фокусированной ультразвуковой аблации при лейомиоме матки // Акуш. и гин. - 2008. - № 4. -С. 24-28.
- Chan A. History of MR guided focused ultrasound: a literature review // White Paper. - 2005. - Vol. 1, № 1.
- FDA Talk Paper: FDA Approves New Device to Treat Uterine Fibroids. // T04-44, October 22, 2004 / Media Inquiries: 301827-6242, Consumer Inquiries: 888-INFO-FDA.
- Fennessy F.M., Tempany C.M. MRI-guided focused ultrasound surgery of uterine leiomyomas // Acad. Radiol. - 2005. -Vol. 12, № 9. - Р 1158-1166.
- Fernanda Chagas Monteiro de Melo, Luana Diacoyannis, Andre Moll, Fernanda Tovar-Moll. Reduction by 98% in uterina myoma volume associated with significant symptom relief after periferal treatment with magnetic resonance imagingguided focused ultrasound surgery // J. Minim. Invasive Gynecol. - 2009. -Vol. 16, № 4. - Р 501-503.
- Healey S., Buzaglo K., Seti L. et al. Ovarian function after uterine artery embolization and hysterectomy // J. Am. Assoc. Gynecol. Laparosc. - 2004. - Vol. 11, № 3. -Р 348-352.
- Hesley G.K., Felmlee J.P., Gebhart J.B. et al. Noninvasive treatment of uterine fibroids: early Mayo Clinic experience with magnetic resonance imaging-guided focused ultrasound // Mayo Clin. Proc. - 2006. - Vol. 81. - Р. 936-942.
- Hindley J., Gedroyc W., Regan L. et al. MR guidance of focused ultrasound therapy of uterine fibroids: early results // Am. J. Roentgenol. - 2004. - Vol. 183, № 6. - Р. 1713-1719.
- Taran F.A., Hesley G.K., Gorny K.R., Stewart E.A. What factors currently limit magnetic resonance-guided focused ultrasound of leiomyomas? A survey conducted at the first international symposium devoted to clinical magnetic resonance-guided focused ultrasound // Fertil. and Steril. - 2009. - Vol. 94, № 1. - Р. 331-334.
- Walker C., Stewart E. Uterine fibroids: the elephant in the room // Science. - 2005. - Vol. 308. - Р. 1589-1592.
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