CORRECTION OF VAGINAL MICROBIOCENOSIS IN WOMEN WITH GESTATIONAL DIABETES MELLITUS
- Authors: ARZHANOVA O.N1, KAPUSTIN R.V1
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Affiliations:
- D.O. Ott Research Institute of Obstetrics and Gynecology, North-Western Branch of the Russian Academy of Medical Science
- Issue: No 6 (2012)
- Pages: 58-62
- Section: Articles
- URL: https://journals.eco-vector.com/0300-9092/article/view/246803
- ID: 246803
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Abstract
Objective. To assess the efficacy of vaginorm-C for the correction of vaginal microbiocenosis in women with gestational diabetes mellitus (GDM). Subjects and methods: The study included 45 pregnant women who formed two comparison groups: 1) 30 pregnant women with dietarily compensated GDM; 2) 15 pregnant women with insulin-compensated GDM. The examination standard included clinical and laboratory studies, determination of vaginal acidity (pH) using Careplan VpH test gloves before and after the study, bacterioscopy, molecular biology (PCR), culture (vaginal smear tests for lactobacteria before and after therapy, study of lactobacteria, and evaluation of perinatal outcomes. Results: Within the first days of use of vaginorm-C, more than half (56%) of the patients of the study groups had objective improvement and reduced clinical symptoms of bacterial vaginosis. The vaginal pH value measured by the Careplan VpH system decreased to normal values (<4.5) in about all (93.4%) women included into the protocol. After treatment, the microflora of vaginal secretions became physiological. Virtually all the pregnant women had term deliveries; all babies were born with Apgar scores of 7—8. There were no postpartum infectious complications in the puerperas. Conclusions: The use of vaginorm-C is a safe and effective method to correct vaginal microbiocenosis in women with gestational diabetes and may be used to treat bacterial vaginosis and to prevent postpartum infections in pregnant women with this pathology.
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About the authors
O. N ARZHANOVA
D.O. Ott Research Institute of Obstetrics and Gynecology, North-Western Branch of the Russian Academy of Medical Science
Email: arjanova_olga@mail.ru
R. V KAPUSTIN
D.O. Ott Research Institute of Obstetrics and Gynecology, North-Western Branch of the Russian Academy of Medical Science
Email: Kapustin.Roman@gmail.com
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