ULTRASTRUCTURAL STUDY OF THE FALLOPIAN TUBAL EPITHELIUM IN REPRODUCTIVE-AGED WOMEN WITH BENIGN TUMORS AND CYSTS OF THE OVARIES


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Abstract

Objective. To evaluate the fimbrial segment of the fallopian tubes in reproductive-aged women with benign tumors and cysts of the ovaries, by using electron microscopy. Subjects and methods. The study enrolled 25 fertile-aged patients with a benign ovarian abnormality. The biopsy specimens of the fimbrial segment of the fallopian tubes, obtained at surgery for the above abnormality, were investigated. Epithelial fragments after respective preparation were looked through an electron microscope. Results. Six patients with unrealized reproductive function were found to have atypical cilia with multiple axonemes and structural abnormalities of the ciliary transit area. Conclusion. It was proposed that the found ultrastructural abnormalities are involved in reproductive dysfunction in the patients. Whether molecular biological diagnostic techniques for ciliopathic infertility may be developed is discussed.

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About the authors

E. I KHARCHENKO

Moscow State University of Medicine and Dentistry; Vidnoye Maternity Home

Email: hadeeva_elmira@inbox.ru

L. V ADAMYAN

Moscow State University of Medicine and Dentistry

Email: adamyanleila@gmail.com

E. E BRAGINA

A.N. Belozersky Research Institute of Physicochemical Biology

Email: bragor@mail.ru

K. D MURVATOV

Main Military Clinical Hospital of Internal Forces, Ministry of Internal Affairs of Russia

Email: mkamol@mail.ru

A. A STEPANYAN

K. N ARSLANYAN

Moscow State University of Medicine and Dentistry

Email: endogyn@mail.ru

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