IMPACT OF PREMATURE FOLLICLE LUTEINIZATION ON THE OUTCOMES OF ASSISTED REPRODUCTIVE TECHNOLOGY PROGRAMS IN GONADOTROPIN-RELEASING HORMONE ANTAGONIST CYCLES


Cite item

Full Text

Open Access Open Access
Restricted Access Access granted
Restricted Access Subscription or Fee Access

Abstract

The review discusses current views on the impact of premature follicle luteinization in gonadotropin-releasing hormone (GnRH) antagonist cycles on the outcomes of assisted reproductive technology programs. GnRH antagonists are widely used by clinicians in their daily practice and are very easy for both a patient and a physician to use; however, premature follicle luteinization, the criterion for which is the rise in progesterone levels on the day of administration of an ovulation trigger, is one of the most common reasons for the lower rate of contraception in the GnRH antagonist cycles.

Full Text

Restricted Access

About the authors

L. V VINOGRADOVA

Academician V.I. Kulakov Research Center of Obstetrics, Gynecology and Perinatology, Ministry of Health and Social Development of Russia

Email: Kalugina-LV@yandex.ru

N. G MISHIYEVA

Academician V.I. Kulakov Research Center of Obstetrics, Gynecology and Perinatology, Ministry of Health and Social Development of Russia

Email: nondoc555@mail.ru

M. V SORVACHEVA

Academician V.I. Kulakov Research Center of Obstetrics, Gynecology and Perinatology, Ministry of Health and Social Development of Russia

Email: Sorvacheva.86@mail.ru

A. N ABUBAKIROV

Academician V.I. Kulakov Research Center of Obstetrics, Gynecology and Perinatology, Ministry of Health and Social Development of Russia

Email: nondoc555@yahoo.com

References

  1. Kolibianakis E.M., Elnashar A.M., Tarlatzis B.C., Devroey P. GnRH antagonists in IVF. Reprod. Biomed. Online. 2005; 10: 705-12.
  2. Ubaldi F., Camus M., Smitz J., Bennink H.C., van Steirteghem A., Devroey P. Premature luteinization in in vitro fertilization cycles using gonadotropin-releasing hormone agonist (GnRH-a) and recombinant follicle-stimulating hormone (FSH) and GnRH-a and urinary FSH. Fertil. Steril. 1996; 66: 27-8.
  3. Назаренко Т.А., Смирнова А.А. Индукция моно и суперовуляции: оценка овариального резерва, ультразвуковой и гормональный мониторинг. Проблемы репродукции. 2004; 1: 36-42.
  4. Смольникова В.Ю., Финогенова Е.Я. Принципы и схемы стимуляции суперовуляции в программе ЭКО и ПЭ. В кн.: Кулаков В.И., Леонов Б.В., Кузьмичев Л.Н., ред. Лечение женского и мужского бесплодия. М.: МИА; 2005: 347-67.
  5. Reissmann T., Schally A.V., Bouchard P., Riethmiiller H., Engel J. The LHRH antagonist cetrorelix: a review. Hum. Reprod. Update. 2000; 6(4): 322-31.
  6. Bosch E., Valencia I., Escudero E., Crespo J., Simon C., Remohi' J., Pellicer A. Premature luteinization during gonadotropin-releasing hormone antagonist cycles and its relationship with in vitro fertilization outcome. Fertil. Steril. 2003; 80(6): 1444-9.
  7. Johnston-MacAnanny E.B., DiLuigi A.J., Engmann L.L., Maier D.B., Benadiva C.A., Nulsen J.C. Selection of first in vitro fertilization cycle stimulation protocol for good prognosis patients: gonadotropin releasing hormone antagonist versus agonist protocols. J. Reprod. Med. 2011; 56(1-2): 12-6.
  8. Kolibianakis E.M., Venetis C.A., Kalogeropoulou L., Papanikolaou E., Tarlatzis B.C. Fixed versus flexible gonadotropin-releasing hormone antagonist administration in in vitro fertilization: a randomized controlled trial. Fertil. Steril. 2011; 95(2): 558-562.
  9. Harada T., Yoshida S., Katagiri C., Takao N., Ikenari T., Toda T. et al. Reduced implantation rat associated with a subtle rise in serum progesterone concentration during the follicular phase of cycles stimulated with a combination of a gonadotrophin-releasing hormone agonist and gonadotrophin. Hum. Reprod. 1995; 10(5): 1060-4.
  10. Olivennes F., Belaisch-Allart J., Emperaire J.C., Dechaud H., Alvarez S., Moreau L. et al. Prospective,randomized, controlled study of in vitro fertilization-embryo transfer with a single dose of a luteinizing hormone-releasing hormone (LH-RH) antagonist (cetrorelix) or a depot formula of an LH-RH agonist (triptorelin). Fertil. Steril. 2000; 73(2): 314-20.
  11. Silverberg K.M., Martin M., Olive D.L., Burns W.N., Schenken R.S. Elevated seru progesterone levels on the day of human chorionic gonadotropin administration in in vitro fertilization cycles do not adversely affect embryo quality. Fertil. Steril. 1994; 61(3): 508-13.
  12. Леонов Б.В., Супряга О.М. Экстракорпоральное оплодотворение и его новые направления в лечении женского бесплодия. М.: МИА; 2000: 717-32.
  13. Кабанова Д.И., Краснопольская К.В., Калугина А.С. Сравнение протоколов стимуляции суперовуляции рекомбинантным у пациенток с синдромом поликистозных яичников в зависимости от исходного состояния яичников. Проблемы репродукции. 2004; 3: 34-41.
  14. Papanikolaou E.G., Kolibianakis E.M., Pozzobon C., Tank P., Tournaye H., Bourgain C. et al. Progesterone rise on the day of human chorionic gonadotropin administration impairs pregnancy outcome in day 3 single-embryo transfer, while has no effect on day 5 single blastocyst transfer. Fertil Steril. 2009; 91(3): 949-52.
  15. Tarlatzis B.C., Fauser B.C., Kolibianakis E.M., Diedrich K., Rombauts L., Devroey P. GnR antagonists in ovarian stimulation for IVF. Hum. Reprod. Update. 2006; 12(4): 333-40.
  16. Younis J.S., Soltsman S., Izhaki I., Radin O., Bar-Ami S., Ben-Ami M. Early and short follicular gonadotropin-releasing hormone antagonist supplementationimproves the meiotic status and competence of retrieved oocytes in in vitro fertilization-embryo transfer cycles. Fertil. Steril. 2010; 94(4): 1350-5.
  17. Fanchin R., de Ziegler D., Taieb J., Hazout A., Frydman R. Premature elevation of plasma progesterone alters pregnancy rates of in vitro fertilization and embryo transfer. Fertil. Steril. 1993; 59(5): 1090-4.
  18. Elnashar A.M. Progesterone rise on the day of HCG administration (premature luteinization) in IVF: an overdue update. J. Assist. Reprod.Genet. 2010; 27(4): 149-55.
  19. Wilcox J., Potter D., Moore M., Ferrande L., Kelly E.; CAP IV Investigator Group. Prospective, randomized trial comparing cetrorelix acetate and ganirelix acetate in a programmed, flexible protocol for premature luteinizing hormone surge prevention in assisted reproductive technologies. Fertil. Steril. 2005; 84(1): 108-17.
  20. Hofmann G.E., Bentzien F., Bergh P.A., Garrisi G.J., Williams M.C., Guzman I., Navot D. Premature luteinization in controlled ovarian hyperstimulation has no adverse effect on oocyte and embryo quality. Fertil. Steril. 1993; 60(4): 675-9.
  21. Bosch E., C. Vidal C. Highly purified hMG versus recombinant FSH in ovarian hyperstimulation with GnRH antagonists-a randomized study. Hum. Reprod. 2008; 23(10): 2346-51.

Supplementary files

Supplementary Files
Action
1. JATS XML

This website uses cookies

You consent to our cookies if you continue to use our website.

About Cookies