ORGAN-SAVING TREATMENT IN YOUNG PATIENTS WITH BREAST CANCER


Cite item

Full Text

Open Access Open Access
Restricted Access Access granted
Restricted Access Subscription or Fee Access

Abstract

Objective. To create a new concept for the surgical treatment of patients with breast cancer (BC) as a component of combination therapy, causing the volume of breast tissue resection to be extended and the radicalism of surgery to be ensured with an optimal aesthetic result. Subject and methods. Fifty-two patients with BC underwent organ-saving treatment with the proper breast tissues being remodulated; the majority of them [27 (51.9%)] had organ-saving surgery with the nipple-areola complex on a lower glandular pedicle being transferred if the tumor was located in the upper quadrants; 13 (25.0%) had mammaplasty with an upper glandular pedicle if the tumor was located in the lower quadrants, and 8 (15.4%) had organ-saving treatment using simple volume replacement, and 4 (7.7%) had this applying a subcutaneous flap of the latissimus dorsi. Results. Twenty-two patients were followed up for 2 years. Survival in Stage 1 BC was 96.9%; there were no local recurrence cases throughout the follow-up. Cosmetic results were assessed, by questioning 24 women; a satisfactory result was noted in 22 patients, which accounted for 91.7%. In addition to achieved good esthetic results, breast reduction surgery is characterized as follows: it facilitates postoperative radiotherapy and simplifies postoperative clinical and instrumental breast examinations. Conclusion. Organ-saving treatment with breast tissue volume displacement and replacement makes it possible to transfer the maximum amount of the gland and to completely restore its volume, shape naturalness, and symmetry, which is important for patient rehabilitation.

Full Text

Restricted Access

About the authors

A. A VOLCHENKO

P.A. Herzen Moscow Oncology Research Institute

Email: mnioi@mail.ru

D. D PAK

P.A. Herzen Moscow Oncology Research Institute

Email: mnioi@mail.ru

F. N USOVA

P.A. Herzen Moscow Oncology Research Institute

Email: mnioi@mail.ru

References

  1. Чиссов В.И., Старинский В.В., Петрова Г.В., ред. Злокачественные новообразования в России в 2010 году (заболеваемость и смертность). М.: МНИОИ им. П.А.Герцена; 2012: 94.
  2. Демидов В.П., Пак Д.Д., Сарибекян Э.К., Джубалиева С.К. Органосохраняющее лечение больных раком молочной железы. В кн.: Онкология на рубеже XXI века. Возможности и перспективы: Материалы Международного форума. Москва, 19-22 октября 1999 г.: Сборник тезисов. М.;1999: 102-3.
  3. Бурлаков А.С. Реконструктивная хирургия в лечении больных раком молочной железы: Автореф. дис.. д-ра мед. наук. М.; 2009: 40-3.
  4. Малыгин Е.Н., Братик А.В., Малыгин С.Е., Аббасов Ф.А., Оганесян К.Р. Результаты наблюдения больных раком молочной железы после реконструктивно-пластических операций, выполненных в течение двадцати лет. Вестник РОНЦ им. Н.Н. Блохина РАМН. 2003; 14(2): 4-7.
  5. Пак Д.Д. Органосохраняющие, функционально-щадящие и реконструктивно-пластические операции при комбинированном лечении больных раком молочной железы: Автореф. дис. д-ра мед. наук. М.; 1999.
  6. American Cancer Society. Cancer Facts and Figures. 2007. http://www.cancer.org/dopwnloads/STT/ CAFF2007PWSecured.pdf
  7. Fisher B., Redmond C., Poisson R., Margolese R., Wolmark N., Wickerham L. et al. Eight-year results of a randomized clinical trial comparing total mastectomy and lumpectomy with or without irradiation in the treatment of breast cancer. N. Engl. J. Med. 1999; 320(13): 822-8.
  8. Audretsch W.P. Reconstruction of the partial mastectomy defect: classification and method. In: Spear S.L., Little J.W., Lippman M.E., Wood W.C., eds. Surgery of the breast: principles and art. Philadelphia: Lippincott Raven; 1998: 155-96.
  9. Veronesi U., Banfi A., Salvadori B., Luini A., Saccozzi R., Zucali R. et al. Breast conservation is the treatment of choice in small breast cancer: long term results of a randomized trial. Eur. J. Cancer. 1990; 26(6): 668-70.
  10. Sacks N.P., Baum M. Primary management of carcinoma of the breast. Lancet. 1993; 342 (8884): 1402-8.
  11. Veronesi U., Salvadori B., Luini A., Banfi A., Zucali R., Del Vecchio M. et al. Conservative treatment of early breast cancer. Long term results of 1232 cases treated with quadrantectomy, axillary dissection and radiotherapy. Ann. Surg. 1990; 211(3): 250-9.
  12. Veronesi U., Voilterrani F., Luini A., Saccozzi R., Del Vecchio M., Zucali R. et al. Quadrantectomy versus lumpectomy for small size breast cancer. Eur. J. Cancer. 1990; 26(6): 671-3.
  13. Agrawal A. Oncoplastic breast cancer surgery. Breast Cancer. 2010; 5(4): 124-6.
  14. Baildam A.D. Oncoplastic surgery of the breast. Br. J. Surg. 2002; 89: 532-3.
  15. Petit J.Y., Rigault L., Zekri A., Le M. Poor esthetic results after conservative treatment of breast cancer. Techniques of partial breast reconstruction. Ann. Chir. Plast. Esthet. 1989; 34(2): 103-8.
  16. O’Rourke S., Galea M.H., Morga n D., Euhus D., Pinder S., Ellis I.O. et al. Local recurrence after simple mastectomy. Br. J. Surg. 1984; 81(3): 386-9.
  17. Clough K.B., Kaufman G.J., Nos C., Buccimazza I., Sarfati I.M. Improving breast cancer surgery: a classification and quadrant per quadrant atlas for oncoplastic surgery. Ann. Surg. Oncol. 2010; 17(5): 1375-91.
  18. Goldman L.D., Goldwyn R.M. Some anatomic considerations of subcutaneous mastectomy. Plast. Reconstr. Surg. 1973; 51(5): 501-5.

Supplementary files

Supplementary Files
Action
1. JATS XML

This website uses cookies

You consent to our cookies if you continue to use our website.

About Cookies