PREDICTION OF THE EFFICIENCY OF SURGICAL TREATMENT FOR INFERTILITY IN WOMEN WITH MINOR FORMS OF EXTERNAL GENITAL ENDOMETRIOSIS


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Abstract

Objective. To assess whether the immunological parameters associated with the activity of humoral immune reactions may be used to predict the efficiency of surgical treatment for infertility in women with minor forms of external genital endometriosis. Subject and methods. Peripheral blood was examined in 33 women with infertility caused by minor forms of external genital endometriosis (a study group) and 19 healthy fertile women (a control group). The levels of B, B1 cells, Th2 lymphocytes and the serum content of IL-4 and IL-6 were determined. Results. In the study group women, the peripheral blood showed increases in the content of B1 lymphocytes and Th2 cells and the serum level of IL-4 and IL-6. The maximum magnitude of immune disorders was associated with the absence of pregnancy after laparoscopy. Conclusion. The level of B1 lymphocytes enables one to predict the efficiency of surgical treatment for infertility in women with minor forms of external endometriosis.

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About the authors

A. K KRASILNIKOVA

V.N. Gorodkov Ivanovo Research Institute of Maternity and Childhood, Ministry of Health of the Russian Federation

Email: ivniimid@ivnet.ru

A. I MALYSHKINA

V.N. Gorodkov Ivanovo Research Institute of Maternity and Childhood, Ministry of Health of the Russian Federation

Email: ivniimid@ivnet.ru

N. YU SOTNIKOVA

V.N. Gorodkov Ivanovo Research Institute of Maternity and Childhood, Ministry of Health of the Russian Federation

Email: niimid.immune@mail.ru

YU. S ANTSIFEROVA

V.N. Gorodkov Ivanovo Research Institute of Maternity and Childhood, Ministry of Health of the Russian Federation

Email: niimid.immune@mail.ru

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