POSSIBILITIES OF THE DIAGNOSIS AND TREATMENT OF THE CERVIX UTERI


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Abstract

Cancer of the cervix uteri (CCU) currently occupies one of the leading places among reproductive system cancers and there is a trend in increased morbidity in many countries of the world. The paper gives data on risk factors for precancer and CCU, describes current methods for the diagnosis of cervical diseases (clinical visual inspection, extended colposcopy, cytology, molecular genetic examination, Digene test, TruScreen, morphological, immunocytochemical, and immunohistochemical studies of the markers p16, Ki67, and anoscopy), and presents the new cytological screening system — the Papanicolau test (Bethesda system). The benefits of drug (immunomodulators) and destructive (ablation and electrical excision) treatments and the possibilities and efficiency of papillomavirus infection and CCU are described in detail.

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About the authors

V. N PRILEPSKAYA

Academician V.I. Kulakov Research Center of Obstetrics, Gynecology, and Perinatology, Ministry of Health of Russia

Email: vprilepskaya@mail.ru
Moscow

E. A KOGAN

Academician V.I. Kulakov Research Center of Obstetrics, Gynecology, and Perinatology, Ministry of Health of Russia

Email: e_kogan@oparina4.ru
Moscow

D. Yu TROFIMOV

Academician V.I. Kulakov Research Center of Obstetrics, Gynecology, and Perinatology, Ministry of Health of Russia

Email: d_trophimov@oparina4.ru
Moscow

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