RATIONALE FOR A PROLONGED LOW-DOSE COMBINED ORAL CONTRACEPTIVE PILL REGIMEN IN THE COMBINATION TREATMENT OF PATIENTS WITH UTERINE MYOMA AND TYPICAL ENDOMETRIAL HYPERPLASIAS


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Abstract

Changes made in the consideration of the etiology and pathogenesis of uterine myoma and endometrial hyperplastic processes, as well as denial of the previously existing overestimated set of cancer alertness could state that prevention, pathogenetic therapy (if their early diagnosis is made), and postoperative anti-recurrence therapy can considerably reduce disease rates and surgical volume. The major protective mechanism of combined oral contraceptive pills is to inhibit ovulation and folliculogenesis, i.e. monthly cyclic processes in the endometrium and myometrium.

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A. L TIKHOMIROV

A.I. Evdokimov Moscow State University of Medicine and Dentistry

V. V KAZENASHEV

A.I. Evdokimov Moscow State University of Medicine and Dentistry

References

  1. Тихомиров А.Л. Миома, патогенетическое обоснование органосохраняющего лечения. Монография. М.; 2013. 319с.
  2. Donnez J., Tomaszewski J., Vazquez F., Vázquez F., Bouchard P., Lemieszczuk B., Baró F. et al.; PEARL II Study Group. Ulipristal acetate versus leuprolide acetate for uterine fibroids. N. Engl. J. Med. 2012; 366(5): 421—32.
  3. Williams A.R., Critchley H.O., Osei J., Ingamells S., Cameron I.T., Han C., Chwalisz K. The effects of the selective progesterone receptor modulator asoprisnil on the morphology of uterine tissues after 3 months treatment in patients with symptomatic uterine leiomyomata. Hum. Reprod. 2007; 22(6): 1696—704.
  4. Тумилович Л.Г., Геворкян М.А. Справочник гинеколога-эндокринолога. М.: Практическая Медицина; 2010. 202с.
  5. Прилепская В.Н., ред. Руководство по контрацепции. М.: МЕДпресс—информ; 2010. 448с.
  6. Viswanathan M., Hartmann K., McKoy N., Stuart G., Rankins N., Thieda P. et al. Management of uterine fibroids: an update of the evidence. Evid. Rep. Technol. Assess. (Full Rep.). 2007; 154: 1—122.

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