PLACE OF LACTOFLORA IN THE CORRECTION OF IMPAIRED VAGINAL MICROBIOCENOSIS IN SEXUALLY ACTIVE WOMEN
- Authors: CHERNOVA N.I1, PERLAMUTROV Y.N1
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Affiliations:
- A.I. Evdokimov Moscow State University of Medicine and Dentistry, Ministry of Health of the Russian Federation
- Issue: No 10 (2013)
- Pages: 104-108
- Section: Articles
- URL: https://journals.eco-vector.com/0300-9092/article/view/247097
- ID: 247097
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Abstract
Background. The widespread use of antibacterial drugs in modern medicine, self-treatment, and sexual promiscuity promote the formation of a large cohort of women with vaginal discomfort complaints caused by impaired microbiocenosis, including the lactoflora. The predominance of lactobacterial strains with a low peroxide-forming potential, which occurs after inadequate courses of antibiotics, antiseptic solutions, decreases the efficiency of their regulating anaerobic exposure and enhances the risk of bacterial vaginosis. Objective. To evaluate the efficiency of local use of gynoflor E in patients with vaginal discharge and discomfort complaints caused by the impaired quantitative and qualitative composition of the normal flora. Subject and methods. Forty patients complaining of vaginal discharge and discomfort were followed up. Their comprehensive examination was made, which involved vaginal discharge pH-metry, amine test with 10% KOH, microscopic and molecular genetic studies with a florocenosis test system. The patients were given gynoflor E tablets vaginally at bedtime once a day for 12 days. Results. Examination of vaginal discharges revealed that the amount of lactobacilli was decreased in all the women regardless of the day of a menstrual cycle. The administration of gynoflor E eliminated subjective and objective symptoms in 95% of the patients. Conclusion. Polymerase chain reaction-based quantification of the flora (florocenosis) convincingly showed that the use of gynoflor E promoted recovery of the lactoflora in 95% of the women.
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About the authors
N. I CHERNOVA
A.I. Evdokimov Moscow State University of Medicine and Dentistry, Ministry of Health of the Russian Federation
Email: d.chernova@mail.ru
Yu. N PERLAMUTROV
A.I. Evdokimov Moscow State University of Medicine and Dentistry, Ministry of Health of the Russian Federation
Email: d.chernova@mail.ru
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