PREGNANCY IN WOMEN WITH SYSTEMIC LUPUS ERYTHEMATOSUS


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Abstract

The review gives the literature data characterizing the autoimmune pathogenesis, diagnosis, clinical course, and treatments of systemic lupus erythematosus (SLE). It discusses the impact of pregnancy on the activity of the disease and the relationship of the pattern and outcome of pregnancy to the activity of SLE, indications for and contraindications to pregnancy prolongation in women with this disease, as well as problems in the prognosis, diagnosis, and management tactics of SLE in pregnant women. Analysis of the data available in the literature suggests that the optimal control of disease activity, the careful planning of pregnancy in conjunction with multidisciplinary monitoring and treatment substantially reduce maternal and infant risks.

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About the authors

E. V FEDOROVA

Academician V.I. Kulakov Research Center of Obstetrics, Gynecology and Perinatology, Ministry of Health of Russia

Email: KatrinaFedorova7@gmail.com
postgraduate of the 1st obstetric pregnancy pathology department 4, Oparin street, Moscow, Russian Federation, 117997

L. V VANKO

Academician V.I. Kulakov Research Center of Obstetrics, Gynecology and Perinatology, Ministry of Health of Russia

Email: lvanko@mail.ru
MD, professor, leading research worker of clinical immunology laboratory 4, Oparin street, Moscow, Russian Federation, 117997

N. I KLIMENCHENKO

Academician V.I. Kulakov Research Center of Obstetrics, Gynecology and Perinatology, Ministry of Health of Russia

Email: natalite@list.ru
PhD, head of the 1st obstetric pregnancy pathology department 4, Oparin street, Moscow, Russian Federation, 117997

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