Management strategy in pregnant women with preterm amniorrhea in preterm pregnancy

Objective. To study perinatal outcomes in patients whose pregnancy was complicated by premature rupture of membranes at 22-35 weeks’ gestation when applying medical expectant pregnancy management strategies. Subject and methods. Eighty-four case histories of deliveries at 22-37 weeks’ gestation, occurring in the Petrozavodsk Republican Perinatal Center in 2009-2012, which were complicated by preterm amniorrhea (PA) and a long dry interval, were analyzed. PA was diagnosed using the AmniSure tests. Results. The investigation has indicated that the medical wait-and-see strategy for PA promote accelerated fetal lung maturation, by increasing the incidence of severe forms of fetal respiratory distress syndrome and reducing the rate of disability in infants in this group. Conclusion. The use of antibiotics could prevent clinically significant infectious complications in the mother and decrease morbidity rates in the newborn infant. The application of current methods for childbirth preparation can reduce the rate of surgical delivery.

preterm labor, preterm amniorrhea, long dry interval, wait-and-see strategy, perinatal outcomes