Aspects of abortion in women with active pulmonary tuberculosis

Objective. To evaluate the specific features of a postabortion period in women with active pulmonary tuberculosis Subject and methods. A retrospective study was performed in 66 women; a control group consisted of 66patients without signs of this disease who wanted to terminate their pregnancy. More than half of the women with tuberculosis had its infiltrative form (56.1%), fibrocavernous tuberculosis (19.7%), pulmonary tuberculomas (19.7%), and focal tuberculosis (4.5%). Lung tissue degeneration was observed in 39.4% of the patients. Results. Intoxication syndrome as a manifestation of the underlying disease was found in 83.4% of the pregnant women, which appeared as fever (51.5%), weakness (57.6%), hyperhidrosis (13.6%), and a concurrence of weakness, sweating, and decreased weight (12.1%). Endometritis developed in 21.2% of the women with pulmonary tuberculosis within the first 3 days after abortion. In the control group, this complication was seen only in 4.5% of the women (x 2 = 6.7; р = 0.009). In the women with active pulmonary tuberculosis, the development of complications after medical abortion is more largely influenced by the absence of antituberculosis therapy (F = 33.4; р = 0.000), the presence of bacterial excretion (F = 21.2; р = 0.000), and antituberculosis drug resistance in mycobacteria and the form and extent of a tuberculosis process in lung tissue (F = 11.2; р = 0.001). Conclusion. As compared to the healthy individuals, the patients with pulmonary tuberculosis more commonly develop postmanipulation complications as endometritis whose development was influenced by both the presence of a tuberculous process and its duration and extent, the absence of specific therapy and drug resistance in the disease pathogen.

tuberculosis, pregnancy termination, complications, endometritis