Efficiency of using epigen intim in combination with a radiowave surgery technique to treat preinvasive cervical neoplasias in reproductive-aged women


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Objective. To study the efficiency of using epigen intim in combination with a radiowave surgery technique to treat preinvasive cervical neoplasias in reproductive-aged women. Subject and methods. After comprehensively examined, 52 patients with H-SIL and c-r in situ of the cervix uteri underwent its electric conization using a radiowave surgery apparatus. To prevent inflammatory complications and to stimulate regeneration, the cervix uteri was treated with epigen intim within 10 days before and after destruction. Results. High-risk human papillomavirus (HPV) was detected in 48 women; 4 were infected with low-risk HPV. After medical therapy in the preoperative period, a reduction in the signs of inflammation was revealed by optical coherence tomography under colposcopic control (OCT colposcopy). Postdestruction healing of the cervix uteri also occurred without inflammatory complications and accompanied by minor bloody or sanious discharge. Posttreatment monitoring showed that 96% of the women were completely healthy. Conclusion. Cervical radiowave destruction in combination with epigen intim can avoid postoperative inflammatory complications and optimize reparative processes after surgical treatment.

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Olga Kachalina

Nizhny Novgorod State Medical Academy

Email: yander24@bk.ru
Ph.D., associate professor of the department of obstetrics and gynecology

Tatiana Kachalina

Nizhny Novgorod State Medical Academy

MD, professor of the department of obstetrics and gynecology

Natalia Shakhova

Nizhny Novgorod State Medical Academy

MD, professor of the department of obstetrics and gynecology

Darya Eliseeva

Nizhny Novgorod State Medical Academy

Email: dd-bundina@yandex.ru
clinical intern of the department of obstetrics and gynecology

Gular Mikailova

Nizhny Novgorod State Medical Academy

Email: g.mikailova90@mail.ru
kyzy, clinical intern of the department of obstetrics and gynecology

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