PREMATURE DELIVERY: ARE THERE PROMISES?


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Abstract

Objective. To evaluate the efficiency and safety of different types of tocolysis during imminent premature delivery. Subject and methods. Women with premature pregnancy and recorded regular uterine contractility at 24-33 weeks’ gestation were divided into 2 groups. Tocolysis was performed using tractocile (atosiban) in Group 1 (n = 35) and gynipral in Group 2 (n = 23). Results. Pregnancy could be prolonged by on an average of 16.9 days in Group 1 and by 10.9 days in Group 2. Tractocil could postpone labor for more than 7 days in 27 pregnant women, which constituted 77% and gynipral could in 11 pregnant women, which was 47.8%. Moreover, the higher frequency of additional administration of tocolytic agents was found in the gynipral group. Conclusion. The use of tractocile is associated with the longer period of preterm pregnancy. And the safety of the agent makes its possible use just in outpatient and first-level inpatient settings, and while transporting to the third-level inpatient settings

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About the authors

Viktor Evseevich Radzinsky

N.E. Bauman City Clinical Hospital Twenty-Nine, Department of Obstetrics and Gynecology with Course of Perinatology, Peoples' Friendship University of Russia

Email: radzinsky@mail.ru
MD, professor, honored scientist of Russian Federation, head of the department of obstetrics and gynecology

Tatyana Vladimirovna Galina

N.E. Bauman City Clinical Hospital Twenty-Nine, Department of Obstetrics and Gynecology with Course of Perinatology, Peoples' Friendship University of Russia

Email: tatiana.galina1@mail.ru
MD, professor. The department of obstetrics and gynecology

Nina Petrovna Kirbasova

I.M. Sechenov First Moscow State Medical University, Ministry of Health of Russia

MD, professor, department of healthcare organization and informatization, prevention of noninfection diseases

Anna Sergeevna Gondarenko

N.E. Bauman City Clinical Hospital Twenty-Nine, Department of Obstetrics and Gynecology with Course of Perinatology, Peoples' Friendship University of Russia

Email: nurkinn@yandex.ru
PhD student. The department of obstetrics and gynecology

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