ROLE OF VITAMIN D IN THE OUTCOMES OF ASSISTED REPRODUCTIVE TECHNOLOGY PROGRAMS


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Abstract

Objective. To make a systems analysis of the data available in the current literature on the effect of vitamin D on the efficiency of assisted reproductive technology (ART) programs and its role in the physiology of the female reproductive system. Subject and methods. The review includes the data of Russian and foreign articles found in the Pubmed database on this topic and published in the past lOyears. Results. The possible mechanisms of vitamin D involvement in embryo implantation processes and the impact of the concentration of this vitamin on the ovarian reserve marker anti-MUllerian hormone are described. The genetically caused vitamin D metabolic features are presented. Conclusion. There is a need for further investigations of the effect of vitamin D on an ovarian response to gonadotropin stimulation and on the outcomes of in vitro fertilization, the occurrence of clinical pregnancy and the birth of a healthy baby in the assisted reproductive technology programs.

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About the authors

Zokhra Mokhamad Sami Naimi

Research Center of Obstetrics, Gynecology, and Perinatology, Ministry of Health of Russia

Email: naimi-zohra@mail.ru
graduate student of department of assisted reproductive technology in treating infertility Moscow 117997, Ac. Oparina str. 4, Russia

Elena Anatolievna Kalinina

Research Center of Obstetrics, Gynecology, and Perinatology, Ministry of Health of Russia

Email: e_kalinina@oparina4.ru
MD, the chief of department of assisted reproductive technology in treating infertility Moscow 117997, Ac. Oparina str. 4, Russia

Andrew Evgenievich Donnikov

Research Center of Obstetrics, Gynecology, and Perinatology, Ministry of Health of Russia

Email: a_donnikov@oparina4.ru
PhD, Senior Researcher of molecul-genetical laboratory Moscow 117997, Ac. Oparina str. 4, Russia

Elena Vladimirovna Kulakova

Research Center of Obstetrics, Gynecology, and Perinatology, Ministry of Health of Russia

Email: evkulakova@mail.ru
PhD, Researcher of department of assisted reproductive technology in treating infertility. Moscow 117997, Ac. Oparina str. 4, Russia

Natalia Vitalievna Dolgushina

Research Center of Obstetrics, Gynecology, and Perinatology, Ministry of Health of Russia

Email: n_dolgushina@oparina4.ru
MD, the chief of the office of scientifically-organizational support. Moscow 117997, Ac. Oparina str. 4, Russia

Dayana Mauluddinovna Skander

I.M. Sechenov First Moscow State Medical University

Email: sk.dayana@mail.ru
student of 6th course 119048, Russia, Moscow, Trubetskaya str. 8/2

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