USE OF HERBAL DOPAMINE MIMETICS IN ADOLESCENTS AND YOUNG WOMEN WITH MENSTRUAL IRREGULARITIES


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Abstract

Functional impairments of the menstrual cycle constitute a significant proportion in the pattern of gynecological diseases in adolescents and young women. Non-hormonal correction is one of the leading therapies of these impairments. Objective. To evaluate the efficiency of using a Vitex agnus-castus-containing drug in adolescents and young women with menstrual irregularities. Subjects and methods. The open-label randomized comparative trial enrolled 80 adolescents and young women with functional impairments of the menstrual cycle who were randomized into two groups receiving cyclodynon (a study group) or a multivitamin complex (a control group) for 6 months. Results. The use of cyclodynon was found to shorten intermenstrual intervals and to improve acyclic bleeding control in patients with oligomenorrhea, to significantly reduce the degree of mastalgia, to improve autonomic function, and to normalize prolactin secretion. Conclusion. The administration of cyclodynon may be regarded as a therapy option in patients with functional menstrual cycle impairments presumptively associated with disorders of prolactin secretion.

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About the authors

Irina V. Kuznetsova

I.M. Sechenov First Moscow State Medical University

Email: ms.smith.ivk@gmail.com
MD, professor. Chief Researcher, Women’s Health Research Center Moscow 119991, Bolshaya Pirogovskaya str. 2 bid. 4, Russia

Yulia B. Uspenskaya

I.M. Sechenov First Moscow State Medical University

MD, a leading researcher, Women’s Health Research Center Moscow 119991, Bolshaya Pirogovskaya str. 2 bid. 4, Russia

Victoria V. Dil

I.M. Sechenov First Moscow State Medical University

PhD student. Women’s Health Research Center Moscow 119991, Bolshaya Pirogovskaya str. 2 bid. 4, Russia

Anna M. Grinyova

I.M. Sechenov First Moscow State Medical University

doctor of the clinic of Obstetrics and Gynecology, V.F. Snegirev UCB N22 Moscow 119991, Bolshaya Pirogovskaya str. 2 bid. 4, Russia

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