DISSOCIATIVE FETAL GROWTH IN TWINS: SERIOUS PATHOLOGY OR NORMAL VARIANT?


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Abstract

Objective. To make a systematic analysis of the data available in the literature on dissociative fetal development during multiple pregnancy. Material and methods. Searches were made in the PubMed database and Russian-language peer-reviewed journals published in the past 15 years. Results. The determinants of fetal growth and the frequency of pregnancy complications in dissociative fetal growth were analyzed. The frequency of the complications in a dissociative twin was shown to substantially increase only if the smaller fetus went beyond the reference values for a given gestational age. Conclusion. Fetal growth restriction syndrome (FGRS) during multiple pregnancy should be diagnosed only when the fetal weight is below the 10h percentile for this gestational age in accordance with a twin-specific nomogram, for twins. Patients with true dissociative twins (FGRS in the smaller fetus) must be followed up only in third-level facilities.

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About the authors

Yu. E Dobrokhotova

Pirogov Russian National Research Medical University

Email: pr.dobrohotova@mail.ru
MD, professor, Head of the Department of Obstetrics and Gynecology, Therapeutic faculty 117437, Russia, Moscow, Ostrovityanova str. I

P. V Kozlov

Pirogov Russian National Research Medical University

Email: kozlovpv@rambler.ru
MD, professor, Department of Obstetrics and Gynecology, Therapeutic faculty 117437, Russia, Moscow, Ostrovityanova str. I

P. A Kuznetsov

Pirogov Russian National Research Medical University

Email: poohsmith@mail.ru
PhD, Department of Obstetrics and Gynecology, Therapeutic faculty 117437, Russia, Moscow, Ostrovityanova str. I

L. S Dzhokhadze

Pirogov Russian National Research Medical University

Email: anton-bl@mail.ru
PhD, Department of Obstetrics and Gynecology, Therapeutic faculty 117437, Russia, Moscow, Ostrovityanova str. I

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