USE OF GEL WITH BACTERIOPHAGES TO SANITIZE THE NASOPHARYNX IN STAPHYLOCOCCUS AUREUS CARRIERS AMONG THE STAFF OF AN OBSTETRIC FACILITY


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Objective. To investigate the efficacy and safety of gel with bacteriophages for nasopharyngeal sanitation in the medical staff of an obstetric facility in order to prevent nosocomial infections caused by S. aureus. Subjects and methods. The investigation enrolled 55 workers from the Neonatal Departments of the Center and a maternity room who had bacteriologically verified S. aureus carriage. The nasopharynx of the medical workers was sanitized with the gel and bacteriophages Otofag (Mikromir, Russia) for 7 days. Results. Microbiological monitoring showed the efficiency of nasopharyngeal sanitation in 94% of the medical workers in the first control test 1-2 weeks after sanitation and in 75.5% of the examinees in the second control test 1-2 months after this procedure. Adverse events were noted in none of the study participants. Conclusion. Otofag showed its efficacy and safety in sanitizing staphylococcus carriers in the obstetric facilities and may be used for periodic preventive sanitation of the nasopharynx of medical staff.

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作者简介

Tatiana Priputnevich

Research Center of Obstetrics, Gynecology, and Perinatology, Ministry of Health of Russia

Email: priputl@gmail.com
MD, Head of research Department of clinical pharmacology and microbiology Moscow 117997, Ac. Oparina str. 4, Russia

Julia Rodchenko

Research Center of Obstetrics, Gynecology, and Perinatology, Ministry of Health of Russia

Email: docrodchenko@mail.ru
physician microbiologist in the Department of clinical pharmacology in Department of clinical pharmacology and microbiology Moscow 117997, Ac. Oparina str. 4, Russia

Lyudmila Lyubasovskaya

Research Center of Obstetrics, Gynecology, and Perinatology, Ministry of Health of Russia

Email: labmik@yandex.ru
PhD, Head of Department of clinical pharmacology in Department of clinical pharmacology and microbiology Moscow 117997, Ac. Oparina str. 4, Russia

Valeriy Chubarov

Research Center of Obstetrics, Gynecology, and Perinatology, Ministry of Health of Russia

Email: v.chubarov@oparina4.ru
physician epidemiologist in the Department of clinical pharmacology in Department of clinical pharmacology and microbiology Moscow 117997, Ac. Oparina str. 4, Russia

Viktor Zubkov

Research Center of Obstetrics, Gynecology, and Perinatology, Ministry of Health of Russia

Email: v_zubkov@oparina4.ru
MD, Head Department of neonatology Moscow 117997, Ac. Oparina str. 4, Russia

Roman Shmakov

Research Center of Obstetrics, Gynecology, and Perinatology, Ministry of Health of Russia

Email: r_shmakov@oparina4.ru
MD, Head Physician Moscow 117997, Ac. Oparina str. 4, Russia

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