Benign breast dysplasia and combined oral contraceptives


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Abstract

Objective. To study current ideas on the role of combined oral contraceptives (COC) in the development of breast cancer. Material and methods. Key words were used to f ind sources on this topic in international databases; 24 sources were selected. Results. There is an update on the role of COC in the development of breast cancer, on the need to individually choose COC having an antiproliferative gestagenic component (dienogest, drospirenone) and on the possibilities to adjust an estrogen dose, without needlessly changing completely COC (ethinyl estradiol 30 or 20 pg), antirecurrent therapy, particularly in women after breast surgery (sector resection) or invasive diagnosis (puncture, biopsy). Conclusion. The timely preclinical diagnosis and targeted prevention of tumors, individual choice of COC, and a possibility to adjust an estrogen dose, as well as antirecurrent therapy are present-day actual measures to reduce female morbidity rates and to improve survival and quality of life.

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About the authors

Vladislava A. Novikova

Kuban State Medical University

Email: vladislavan@mail.ru
MD, professor of the Department of Obstetrics, Gynecology and Perinatology, Faculty of Postgraduate Education

Grigory A. Penzhoyan

Kuban State Medical University; Territorial Clinical Hospital Two

Email: pga05@mail.ru
MD, professor, Head of the Department of Obstetrics, Gynecology and Perinatology, Department of Obstetrics, Gynecology and Perinatology, Faculty of Postgraduate Education

Oleg K. Fedorovich

Kuban State Medical University

Email: olegfedo@mail.ru
MD, professor of the Department of Obstetrics, Gynecology and Perinatology, Faculty of postgraduate Education

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