THE BACTERIAL AND ANTIMICROBIAL COMPONENTS OF NONSPECIFIC VAGINAL IMMUNITY IN PREGNANT WOMEN WITH RECURRENT BACTERIAL VAGINOSIS
- 作者: Podgornaya A.V.1, Makhmutkhodzhaev A.S.1
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隶属关系:
- 期: 编号 12 (2016)
- 页面: 66-69
- 栏目: Articles
- URL: https://journals.eco-vector.com/0300-9092/article/view/247825
- ID: 247825
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详细
Objective. To estimate the level of β-defensin-2 and the composition of the vaginal microflora in pregnant women with recurrent bacterial vaginosis. Subjects and methods. The study included 40 pregnant women with recurrent bacterial vaginosis, in whom the manifestations of the disease, the level of β-defensin-2, and the characteristics of the bacterial flora in the vagina were assessed. Forty healthy pregnant women served as a comparison group. Results. The patients with recurrent bacterial vaginosis showed decreased vaginal β-defensin-2 concentrations that were accompanied by the increased relative content of anaerobic microorganisms in the presence of persistent subclinical signs of dysbiosis. Conclusion. The decreased production of β-defensin-2 and the predominance of certain types of anaerobic microorganisms in the vagina of pregnant women can cause recurrent bacterial vaginosis.
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作者简介
Anna Podgornaya
Assistant of the Department of Obstetrics and Gynecology, Department of Professional Development and Retraining, Siberian State Medical University, Ministry of Health of Russia. 634050, Russia, Tomsk, Moskovsky tract 2
Alisher Makhmutkhodzhaev
Email: alisher_sh_m@mail.ru
MD, Head of the Department of Obstetrics and Gynecology, Department of Professional Development and Retraining, Siberian State Medical University, Ministry of Health of Russia. 634050, Russia, Tomsk, Moskovsky tract 2
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