Bacterial vaginosis and aerobic vaginitis as major vaginal microflora balance disorders: Diagnostic and therapeutic characteristics


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Abstract

Objective. To carry out a systematic analysis of the data available in the current literature on the clinical significance and characteristics of the diagnosis and therapy of major vaginal microflora disorders, such as of bacterial vaginosis (BV) and aerobic vaginitis (AV). Material and methods. The review includes the data of foreign and Russian articles published in the past 10 years and found in electron bibliographic databases on this topic. Results. The vaginal microflora balance disorders including BV and AV were described to have a negative impact on female reproductive function. Similarities of and differences between these two conditions were analyzed. Evidence-based approaches to diagnosing and treating BV and AV were given. Conclusion. BV and AV can cause abnormal vaginal discharge and lead to diseases of the genitourinary system and infectious complications of pregnancy. Microscopic vaginal discharge examination is a main laboratory method for the diagnosis of these diseases. Treatment for BV and AV is to inhibit overgrowth of opportunistic bacterial pathogens associated with these conditions.

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About the authors

Alevtina Mikhailovna Savicheva

D.O. Ott Research Institute of Obstetrics, Gynecology and Reproductology

Email: savitcheva@mail.ru
MD, Professor, Head of Laboratory of Microbiology

Natalia Igorevna Tapilskaya

St Petersburg State Pediatric Medical University

MD, Professor of the Department of Obstetrics and Gynecology

Elena Vasilyevna Shipitsyna

D.O. Ott Research Institute of Obstetrics, Gynecology and Reproductology

PhD, Senior Researcher, Laboratory of Microbiology

Nadezhda Evgenyevna Vorobyeva

D.O. Ott Research Institute of Obstetrics, Gynecology and Reproductology

Researcher, Department of Endocrinology of Reproduction

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