The health status of a baby born to a heart transplant woman: A dinical case


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Abstract

Background. The number of pregnancies following solid organ transplantation is increasing all over the world. There are now few articles in the literature on the health status of babies born to mothers with transplanted organs. A case report. The paper presents a clinical observation of the health status of an infant born to a heart transplant patient at his birth and at the age of 5 years, whose prenatal development proceeded during maternal use of azathioprine and tacrolimus. Complex clinical and laboratory examination did not reveal gross malformations in the baby. His severe status at birth and during neonatal period is due to prematurity, congenital pneumonia, and birth asphyxia. Conclusion. The pregnancy outcomes may be favorable in women after heart transplantation. The given clinical case shows the absence of gross malformation in the child and the correspondence of his psycho-motor and physical development with age. However, there is a need for investigations using a larger sample of infants born to mothers with transplanted organs in order to elaborate tactics of their management in the neonatal period and at an older age.

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About the authors

Ekaterina Aleksandrovna Shatalova

Research Center of Obstetrics, Gynecology, and Perinatology, Ministry of Health of Russia

Email: e_shatalova@oparina4.ru
post-graduate student of the Department of Anesthesiology, Intensive Care and Neonatal Intensive Care

Viktor Vasilievich Zubkov

Research Center of Obstetrics, Gynecology, and Perinatology, Ministry of Health of Russia; I.M. Sechenov First Moscow State Medical University, Ministry of Health of Russia

Email: v_zubkov@oparina4.ru
MD, head of the department. Department of neonatology and pediatrics; Professor of the Department of Neonatology

Natalia Fedorovna Kravchenko

Research Center of Obstetrics, Gynecology, and Perinatology, Ministry of Health of Russia

Email: n_kravchenko@oparina4.ru
Ph.D., Senior Researcher of the 1st Obstetric Department of the Pathology of Pregnancy

Lyudmila Viktorovna Vanko

Research Center of Obstetrics, Gynecology, and Perinatology, Ministry of Health of Russia

Email: l_Vanko@oparina4.ru
MD, Professor, Leading Researcher, Laboratory of Clinical Immunology

Oleg Vadimovich Ionov

Research Center of Obstetrics, Gynecology, and Perinatology, Ministry of Health of Russia

Email: o_ionov@oparina4.ru
Candidate of Medical Science, Head. Department of resuscitation and intensive care of newborns

Irina Ivanovna Ryumina

Research Center of Obstetrics, Gynecology, and Perinatology, Ministry of Health of Russia; I.M. Sechenov First Moscow State Medical University, Ministry of Health of Russia

Email: i_ryumina@oparina4.ru
MD, head of the department. Department of Pathology of Newborns and Premature Children; Professor of the Department of Neonatology

Anna Vladimirovna Degtyareva

Research Center of Obstetrics, Gynecology, and Perinatology, Ministry of Health of Russia; I.M. Sechenov First Moscow State Medical University, Ministry of Health of Russia

Email: a_degtyareva@oparina4.ru
MD, a pediatrician of the highest category, the head of the scientific advisory pediatric department of the; Professor of the Department of Neonatology

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