Influence of seminal plasma on female reproductive function


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Abstract

Objective. To carry out a systematic analysis of the data available in the current literature on the influence of seminal plasma on the occurrence of pregnancy and its role in the physiology of the female reproductive system. Material and methods. The review includes the data of foreign and Russian articles published in the past 10 years and found in Pubmed on this topic. Results. The paper reviews publications concerning the study of the influence of seminal plasma on the female reproductive tract and considers signaling molecules and various mechanisms of their action. Conclusion. A deep understanding of the molecular and cellular bases of the effect of seminal plasma on the formation of a maternal optimal immune response that is necessary for the successful realization of reproductive function will be able allow to elaborate new personalized approaches to treating infertility and pregnancy disorders and planning a family.

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About the authors

Tatyana Vladimirovna Dontsova

Research Center of Obstetrics, Gynecology, and Perinatology, Ministry of Health of Russia

Email: dr.dontsova@gmail.com
postgraduate student of the Department of Auxiliary Technologies in Infertility Treatment

Elena Anatolievna Kalinina

Research Center of Obstetrics, Gynecology, and Perinatology, Ministry of Health of Russia

Email: e_kalinina@oparina4.ru
MD, Head of the Department of Auxiliary Technologies in Infertility Treatment

Marina Arkadevna Nikolaeva

Research Center of Obstetrics, Gynecology, and Perinatology, Ministry of Health of Russia

Email: nikolaeva_ma@mail.ru
Doctor of Biological Sciences, Leading Researcher of the Laboratory of Clinical Immunology

Alina Anatolievna Babayan

Research Center of Obstetrics, Gynecology, and Perinatology, Ministry of Health of Russia

Email: alinababayan@yandex.ru
doctor of the Department of Auxiliary Technologies in Infertility Treatment

Kamila Ullubievna Alieva

Research Center of Obstetrics, Gynecology, and Perinatology, Ministry of Health of Russia

Email: kaya79@mail.ru
Ph.D., scientific employee of the Department of Auxiliary Technologies in Infertility Treatment

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